FSHR Polyclonal Antibody | Invitrogen PA5-33548 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

FSHR Polyclonal Antibody

catalog :

PA5-33548

quantity :

50 ug

price :

US 485.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

domestic goat, human, rat, bovine, pigs , domestic sheep, domestic rabbit, domestic horse

application :

immunohistochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

FSHR Polyclonal Antibody

Catalog # :

PA5-33548

Quantity :

50 ug

Price :

US 485.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bat, Bovine, Equine, Goat, Human, Non-human primate, Ovine, Porcine, Rabbit, Rat

Applications :

Immunohistochemistry (Paraffin): 10-20 ug/mL

Species :

Bat, Bovine, Equine, Goat, Human, Non-human primate, Ovine, Porcine, Rabbit, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Follicle-Stimulating Hormone Receptor (FSHR) expression has been reported in ovary, uterus, and testis. ESTs have been isolated from testis libraries. G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist. All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms. An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors. Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs. This turn-off activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates. Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.

Immunogen :

Synthetic 18 amino acid peptide from N-terminal extracellular domain of human FSHR.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 10-20 ug/mL

Aliases :

follicle stimulating hormone receptor; follicle-stimulating hormone receptor; Follitropin receptor; FSH receptor; Fshr; FSH-R; FSHR1; FSHRO; LGR1; ODG1