This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MARK1 Polyclonal Antibody
catalog :
PA5-32914
quantity :
50 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, dogs, bovine, domestic rabbit
application :
immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
MARK1 Polyclonal Antibody
Catalog # :
PA5-32914
Quantity :
50 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bat, Bovine, Canine, Human, Non-human primate, Rabbit
Applications :
Immunohistochemistry (Paraffin): 5 ug/mL
Species :
Bat, Bovine, Canine, Human, Non-human primate, Rabbit
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
MARK1 (MARK) is a serine/threonine kinase which is involved in cytoskeletal organization and biogenesis. Involved in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. MARK1 is involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity and microtubule dynamics, possibly by phosphorylating and regulating DCX. Also acts as a positive regulator of the Wnt signaling pathway, probably by mediating phosphorylation of dishevelled proteins (DVL1, DVL2 and/or DVL3).
Immunogen :
Synthetic 18 amino acid peptide from N-terminus of human MARK1.
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 5 ug/mL
Aliases :
AW491150; B930025N23Rik; ELKL motif serine/threonine-protein kinase 3; ELKL motif serine-threonine protein kinase 3; Emk3; KIAA1477; MAP/microtubule affinity regulating kinase 1; MAP/microtubule affinity-regulating kinase 1; MARK; MARK1; mark1 {ECO:0000312; microtubule affinity regulating kinase 1; mKIAA1477; mPar-1c; PAR1 homolog c; Par1c; Par-1c; RGD:619882}; serine/threonine-protein kinase MARK1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA