MMP15 Polyclonal Antibody | Invitrogen PA5-32501 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

MMP15 Polyclonal Antibody

catalog :

PA5-32501

quantity :

500 uL

price :

US 404.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

product information

Product Type :

Antibody

Product Name :

MMP15 Polyclonal Antibody

Catalog # :

PA5-32501

Quantity :

500 uL

Price :

US 404.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:50

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

MMPs are a group of enzymes involved in matrix degradation. Of the sixteen members of matrix metalloproteinase family ten exist in soluble form whereas MT-MMPs exist as integral membrane proteins. MT1-MMP, MT2-MMP, MT3-MMP also known as MMP14, MMP15, MMP16 respectively contain a C-terminal transmembrane domain anchoring them to the cell surface. They have an 8 amino acid insert in their catalytic domain. MT1-MMP cleaves progelatinase A (MMP-2) and progelatinase B to their active forms. MT2-MMP plays a minor role in activation of pro-MMP-2 to its active form in breast carcinomas. Coexpression of MT1-MMP and MT2-MMp in advanced stages of breast carcinomas is indicative of possible involvement of MT2-MMP in its metastasis.

Immunogen :

Synthetic peptide from the catalytic domain of mouse MMP-15 / MT2-MMP protein

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 1:50

Aliases :

AI503551; matrix metallo protease; matrix metallopeptidase 15; matrix metallopeptidase 15 (membrane-inserted); matrix metalloproteinase 15; matrix metalloproteinase 15 (membrane-inserted); matrix metalloproteinase-15; Membrane type 2-MMP; membrane-type matrix metalloproteinase 2; Membrane-type-2 matrix metalloproteinase; MMP; Mmp15; MMP-15; MMPs; MT2MMP; MT2-MMP; MT-MMP 2; MTMMP2; SMCP-2