F4/80 Polyclonal Antibody | Invitrogen PA5-32399 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

F4/80 Polyclonal Antibody

catalog :

PA5-32399

quantity :

500 µL

price :

US 470

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

mouse

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 11

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:100; loading ...; fig 5	Zhang Y, Yu J, Grachtchouk V, Qin T, Lumeng C, Sartor M, et al. Genomic binding of PAX8-PPARG fusion protein regulates cancer-related pathways and alters the immune landscape of thyroid cancer. Oncotarget. 2017;8:5761-5773 pubmed publisher
	Heissig B, Salama Y, Tateno M, Takahashi S, Hattori K. siRNA against CD40 delivered via a fungal recognition receptor ameliorates murine acute graft-versus-host disease. EJHaem. 2022;3:849-861 pubmed publisher
	Starlinger J, Sarahrudi K, Kecht M, Koerbler F, Pietschmann P, Aharinejad S. The influence of M-CSF on fracture healing in a mouse model. Sci Rep. 2021;11:22326 pubmed publisher
	Genovese P, Patel A, Ziemkiewicz N, Paoli A, Bruns J, Case N, et al. Co-delivery of fibrin-laminin hydrogel with mesenchymal stem cell spheroids supports skeletal muscle regeneration following trauma. J Tissue Eng Regen Med. 2021;15:1131-1143 pubmed publisher
	Huang R, Hu Z, Chen X, Cao Y, Li H, Zhang H, et al. The Transcription Factor SUB1 Is a Master Regulator of the Macrophage TLR Response in Atherosclerosis. Adv Sci (Weinh). 2021;8:e2004162 pubmed publisher
	Kaplan M, Kalajzic Z, Choi T, Maleeh I, Ricupero C, Skelton M, et al. The role of inhibition of osteocyte apoptosis in mediating orthodontic tooth movement and periodontal remodeling: a pilot study. Prog Orthod. 2021;22:21 pubmed publisher
	Youngblood R, Flesher C, Delproposto J, Baker N, Neeley C, Li F, et al. Regulation of adipose tissue inflammation and systemic metabolism in murine obesity by polymer implants loaded with lentiviral vectors encoding human interleukin-4. Biotechnol Bioeng. 2020;117:3891-3901 pubmed publisher
	Gu L, Larson Casey J, Andrabi S, Lee J, Meza Perez S, Randall T, et al. Mitochondrial calcium uniporter regulates PGC-1α expression to mediate metabolic reprogramming in pulmonary fibrosis. Redox Biol. 2019;26:101307 pubmed publisher
	Grey Z, Howie R, Durham E, Hall S, Helke K, Steed M, et al. Sub-clinical dose of bone morphogenetic protein-2 does not precipitate rampant, sustained inflammatory response in bone wound healing. Wound Repair Regen. 2019;27:335-344 pubmed publisher
	Heard M, Melnyk S, Simmen F, Yang Y, Pabona J, Simmen R. High-Fat Diet Promotion of Endometriosis in an Immunocompetent Mouse Model is Associated With Altered Peripheral and Ectopic Lesion Redox and Inflammatory Status. Endocrinology. 2016;157:2870-82 pubmed publisher
	Brown A, Simmen R, Raj V, Van T, MacLeod S, Simmen F. KrÃ¼ppel-like factor 9 (KLF9) prevents colorectal cancer through inhibition of interferon-related signaling. Carcinogenesis. 2015;36:946-55 pubmed publisher

product information

Product Type :

Antibody

Product Name :

F4/80 Polyclonal Antibody

Catalog # :

PA5-32399

Quantity :

500 µL

Price :

US 470

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse

Applications :

Immunohistochemistry (Paraffin): 1:100

Species :

Mouse

Isotype :

IgG

Storage :

4° C, do not freeze

Description :

F4/80 antigen is a 160 kDa cell surface glycoprotein that is a member of the EGF TM7 family of proteins and shares 68% overall amino acid identity with human EGF module containing mucin like hormone receptor 1 (EMR1). Expression of F4/80 is heterogeneous and is reported to vary during macrophage maturation and activation. The F4/80 antigen is expressed on a wide range of mature tissue macrophages including Kupffer cells, Langerhans, microglia, macrophages located in the gut lamina propria, peritoneal cavity, lung, thymus, bone marrow stroma and macrophages in the red pulp of the spleen. F4/80 expression has also been reported on a subpopulation of dendritic cells but is absent from macrophages located in T cell areas of the spleen and lymph node. The ligands and biological functions of the F4/80 antigen have not yet been determined but recent studies suggest a role for F4/80 in the generation of efferent CD8+ve regulatory T cells.

Immunogen :

Synthetic peptide derived from N-terminus of mouse F4/80 protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100

Aliases :

ADGRE1; Adhesion G protein-coupled receptor E1; Adhesion G protein-coupled receptor E2; cell surface glycoprotein EMR1; cell surface glycoprotein F4/80; DD7A5-7; EGF-like module containing, mucin-like, hormone receptor-like 1; EGF-like module containing, mucin-like, hormone receptor-like sequence 1; EGF-like module receptor 1; EGF-like module-containing mucin-like hormone receptor-like 1; EGF-TM7; Emr1; EMR1 hormone receptor; F4/80; Gpf480; Ly71; lymphocyte antigen 71; TM7LN3