Influenza A NP Polyclonal Antibody | Invitrogen PA5-32242 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Influenza A NP Polyclonal Antibody

catalog :

PA5-32242

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 22

Reference
Waqas F, Shehata M, Elgaher W, Lacour A, Kurmasheva N, Begnini F, et al. NRF2 activators inhibit influenza A virus replication by interfering with nucleo-cytoplasmic export of viral RNPs in an NRF2-independent manner. PLoS Pathog. 2023;19:e1011506 pubmed publisher
Hu K, Palmieri E, Samnuan K, Ricchetti B, Oldrini D, McKay P, et al. Generalized Modules for Membrane Antigens (GMMA), an outer membrane vesicle-based vaccine platform, for efficient viral antigen delivery. J Extracell Vesicles. 2022;11:e12247 pubmed publisher
Bonifacio J, Williams N, Garnier L, Hugues S, Schmolke M, Mazel Sanchez B. Optimizing the Live Attenuated Influenza A Vaccine Backbone for High-Risk Patient Groups. J Virol. 2022;96:e0087122 pubmed publisher
Kim J, Bryant H, Fiedler E, Cao T, Rayner J. Real-time tracking of bioluminescent influenza A virus infection in mice. Sci Rep. 2022;12:3152 pubmed publisher
Bell T, Velappan N, Gleasner C, Xie G, Starkenburg S, Waldo G, et al. Nonclassical autophagy activation pathways are essential for production of infectious Influenza A virus in vitro. Mol Microbiol. 2022;117:508-524 pubmed publisher
Christgen S, Place D, Zheng M, Briard B, Yamamoto M, Kanneganti T. The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice. Eur J Immunol. 2022;52:285-296 pubmed publisher
Kesavardhana S, Samir P, Zheng M, Malireddi R, Karki R, Sharma B, et al. DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response. J Biol Chem. 2021;296:100579 pubmed publisher
Boal Carvalho I, Mazel Sanchez B, Silva F, Garnier L, Yildiz S, Bonifacio J, et al. Influenza A viruses limit NLRP3-NEK7-complex formation and pyroptosis in human macrophages. EMBO Rep. 2020;:e50421 pubmed publisher
Goulding L, Yang J, Jiang Z, Zhang H, Lea D, Emes R, et al. Thapsigargin at Non-Cytotoxic Levels Induces a Potent Host Antiviral Response that Blocks Influenza A Virus Replication. Viruses. 2020;12: pubmed publisher
Wacquiez A, Coste F, Kut E, Gaudon V, Trapp S, Castaing B, et al. Structure and Sequence Determinants Governing the Interactions of RNAs with Influenza A Virus Non-Structural Protein NS1. Viruses. 2020;12: pubmed publisher
Zheng A, Sun W, Xiong X, Freyn A, Peukes J, Strohmeier S, et al. Enhancing Neuraminidase Immunogenicity of Influenza A Viruses by Rewiring RNA Packaging Signals. J Virol. 2020;94: pubmed publisher
Tuku B, Stanelle Bertram S, Sellau J, Beck S, Bai T, Kouassi N, et al. Testosterone Protects Against Severe Influenza by Reducing the Pro-Inflammatory Cytokine Response in the Murine Lung. Front Immunol. 2020;11:697 pubmed publisher
Beck S, Zickler M, Pinho Dos Reis V, Gunther T, Grundhoff A, Reilly P, et al. ANP32B Deficiency Protects Mice From Lethal Influenza A Virus Challenge by Dampening the Host Immune Response. Front Immunol. 2020;11:450 pubmed publisher
Xu N, Yang J, Zheng B, Zhang Y, Cao Y, Huan C, et al. The Pyrimidine Analog FNC Potently Inhibits the Replication of Multiple Enteroviruses. J Virol. 2020;94: pubmed publisher
Broecker F, Zheng A, Suntronwong N, Sun W, Bailey M, Krammer F, et al. Extending the Stalk Enhances Immunogenicity of the Influenza Virus Neuraminidase. J Virol. 2019;93: pubmed publisher
Tome Amat J, Ramos I, Amanor F, Fernandez Sesma A, Ashour J. Influenza A Virus Utilizes Low-Affinity, High-Avidity Interactions with the Nuclear Import Machinery To Ensure Infection and Immune Evasion. J Virol. 2019;93: pubmed publisher
Broecker F, Liu S, Sun W, Krammer F, Simon V, Palese P. Immunodominance of Antigenic Site B in the Hemagglutinin of the Current H3N2 Influenza Virus in Humans and Mice. J Virol. 2018;92: pubmed publisher
Zhong G, Le M, Lopes T, Halfmann P, Hatta M, Fan S, et al. Mutations in the PA Protein of Avian H5N1 Influenza Viruses Affect Polymerase Activity and Mouse Virulence. J Virol. 2018;92: pubmed publisher
Kesavardhana S, Kuriakose T, Guy C, Samir P, Malireddi R, Mishra A, et al. ZBP1/DAI ubiquitination and sensing of influenza vRNPs activate programmed cell death. J Exp Med. 2017;214:2217-2229 pubmed publisher
Moreira É, Locher S, Kolesnikova L, Bolte H, Aydillo T, Garcia Sastre A, et al. Synthetically derived bat influenza A-like viruses reveal a cell type- but not species-specific tropism. Proc Natl Acad Sci U S A. 2016;113:12797-12802 pubmed publisher
Moreira É, Weber A, Bolte H, Kolesnikova L, Giese S, Lakdawala S, et al. A conserved influenza A virus nucleoprotein code controls specific viral genome packaging. Nat Commun. 2016;7:12861 pubmed publisher
Parvin R, Shehata A, Heenemann K, Gac M, Rueckner A, Halami M, et al. Differential replication properties among H9N2 avian influenza viruses of Eurasian origin. Vet Res. 2015;46:75 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Influenza A NP Polyclonal Antibody

Catalog # :

PA5-32242

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Virus

Applications :

ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:5,000-1:20,000

Species :

Virus

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The nucleoprotein (NP) of Influenza A virus encapsidates the negative strand of the viral RNA and is essential for replicative transcription. It may also be involved in other essential functions throughout the virus life cycle. As well as binding ssRNA, NP is able to self associate to form large oligomeric complexes. NP is able to interact with a variety of other macromolecules of both viral and cellular origins. It binds the PB1 and PB2 subunits of the polymerase and the matrix protein M1. 'NP has also been shown to interact with at least four cellular polypeptide families: nuclear import receptors of the importin class, filamentous (F) actin, the nuclear export receptor CRM1 and a DEAD box helicase BAT1/UAP56' (Portela et al 2002).

Immunogen :

Recombinant protein fragment of Influenza A virus NP (A/WSN/1933(H1N1))

Format :

Liquid

Applications w/Dilutions :

ELISA: Assay-dependent, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): Assay-dependent, Western Blot: 1:5,000-1:20,000

Aliases :

Influenza nucleoprotein