Influenza A M2 Polyclonal Antibody | Invitrogen PA5-32233 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Influenza A M2 Polyclonal Antibody

catalog :

PA5-32233

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

western blot, immunocytochemistry

citations: 4

Reference
Bogdanow B, Wang X, Eichelbaum K, Sadewasser A, Husic I, Paki K, et al. The dynamic proteome of influenza A virus infection identifies M segment splicing as a host range determinant. Nat Commun. 2019;10:5518 pubmed publisher
Chen A, Dong J, Yuan X, Bo H, Li S, Wang C, et al. Anti-H7N9 avian influenza A virus activity of interferon in pseudostratified human airway epithelium cell cultures. Virol J. 2019;16:44 pubmed publisher
Rahim M, Klewes L, Zahedi Amiri A, Mai S, Coombs K. Global Interactomics Connect Nuclear Mitotic Apparatus Protein NUMA1 to Influenza Virus Maturation. Viruses. 2018;10: pubmed publisher
Yángüez E, Hunziker A, Dobay M, Yildiz S, Schading S, Elshina E, et al. Phosphoproteomic-based kinase profiling early in influenza virus infection identifies GRK2 as antiviral drug target. Nat Commun. 2018;9:3679 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Influenza A M2 Polyclonal Antibody

Catalog # :

PA5-32233

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Virus

Applications :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Species :

Virus

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Influenza A virus is an enveloped virus encoding 10 polypeptides. RNA segment 7 encodes for two proteins: M1 (matrix 1) and M2 (matrix 2). M1 protein is encoded by an mRNA that is colinear, while M2 protein is synthesized from spliced mRNA. M2 protein is a transmembrane protein composed of three Domains: 1) 24 residues representing the N-terminal region, 2) 19 hydro-phobic residues that serve as a membrane anchor, and 3) 54 residues near the C-terminal in the cytoplasmic domain. The M2 protein has been found to play a role in Influenza replication and assembly of virion particles. Further experimentation has demonstrated that this protein is an acid-activated ion channel for virus replication.

Immunogen :

Recombinant protein fragment of influenza A virus M2 (A/Puerto Rico/8/1934(H1N1))

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Aliases :

Influenza M2