Influenza A PA Polyclonal Antibody | Invitrogen PA5-32223 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Influenza A PA Polyclonal Antibody

catalog :

PA5-32223

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

application :

western blot, immunocytochemistry

citations: 2

Reference
Kim J, Bryant H, Fiedler E, Cao T, Rayner J. Real-time tracking of bioluminescent influenza A virus infection in mice. Sci Rep. 2022;12:3152 pubmed publisher
Miura M, Chen H. CUT&RUN detects distinct DNA footprints of RNA polymerase II near the transcription start sites. Chromosome Res. 2020;28:381-393 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Influenza A PA Polyclonal Antibody

Catalog # :

PA5-32223

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Virus

Applications :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Species :

Virus

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Influenza viruses consists of three types (Influenza A, B, and C), which make up three of the five genera in the Orthomyxoviridae family. Commonly know as the flu, influenza strains can affect both birds and mammals. Influenza strains form roughly spherical particles and are similar in composition with viral envelope containing two main types of glycoproteins (hemagglutinin and neuraminidase), wrapped around the central core of the viral RNA genome and other viral proteins that package and protect the RNA. Unusually for a virus, the influenzavirus genome is not a single piece of nucleic acid; rather a seven to eight segmented fragments of negative-sense RNA with each fragment expressing different viral proteins. Influenza spreads seasonally, resulting in about three to five million yearly cases of severe illness and about 250,000 to 500,000 deaths annually or into the millions in pandemic years. Influenza A virus contains eight single stranded, negative sense RNAs. Each RNA is associated with viral RNA-dependent RNA polymerase which consists of PA, PB1 and PB2 proteins. Recent reports indicate the involvement of PA in 'cap-snatching' mechanism via its endonuclease activity which is essential for cRNA-dependent viral RNA synthesis.

Immunogen :

Recombinant protein fragment of influenza A virus PA (A/Puerto Rico/8/1934(H1N1))

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Aliases :

Influenza PA