E-cadherin Polyclonal Antibody | Invitrogen PA5-32178 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

E-cadherin Polyclonal Antibody

catalog :

PA5-32178

quantity :

100 uL

price :

US 558.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 16

Reference
Lan Z, Sun F, Chen C, Niu L, Shi J, Zhang W. CircPRDM5 inhibits the proliferation, migration, invasion, and glucose metabolism of gastric cancer cells by reducing GCNT4 expression in a miR-485-3p-dependent manner. Kaohsiung J Med Sci. 2024;40:231-243 pubmed publisher
Zhao Y, Chen J, Xu S, Chen Y. CircMETTL15 induces TMTC3 production by absorbing miR-944 to promote hepatocellular carcinoma cell malignancy. J Biochem Mol Toxicol. 2024;38:e23567 pubmed publisher
Tanaka K, Kawai S, Fujii E, Yano M, Miyayama T, Nakano K, et al. Development of rat duodenal monolayer model with effective barrier function from rat organoids for ADME assay. Sci Rep. 2023;13:12130 pubmed publisher
Jafari N, Rohn J. An immunoresponsive three-dimensional urine-tolerant human urothelial model to study urinary tract infection. Front Cell Infect Microbiol. 2023;13:1128132 pubmed publisher
Shang J, Lin L, Huang X, Zhou L, Huang Q. Re-expression of circ_0043610 contributes to trophoblast dysfunction through the miR-558/RYBP pathway in preeclampsia. Endocr J. 2022;69:1373-1385 pubmed publisher
Wang H, Luo Y, Chu Z, Ni T, Ou S, Dai X, et al. Poria Acid, Triterpenoids Extracted from Poria cocos, Inhibits the Invasion and Metastasis of Gastric Cancer Cells. Molecules. 2022;27: pubmed publisher
Li D, Fu Z, Dong C, Song Y. Downregulation of circATXN7 represses non-small cell lung cancer growth by releasing miR-7-5p. Thorac Cancer. 2022;13:1597-1610 pubmed publisher
Chu Z, Luo Y, Ni T, Zhu M, Feng X, Liu Y, et al. Betulonic Acid, as One of the Active Components of the Celastrus orbiculatus Extract, Inhibits the Invasion and Metastasis of Gastric Cancer Cells by Mediating Cytoskeleton Rearrangement In Vitro. Molecules. 2022;27: pubmed publisher
Abraham H, Ulintz P, Goo L, Yates J, Little A, Bao L, et al. RhoC Modulates Cell Junctions and Type I Interferon Response in Aggressive Breast Cancers. Front Oncol. 2021;11:712041 pubmed publisher
Batsche E, Yi J, Mauger O, Kornobis E, Hopkins B, Hanmer Lloyd C, et al. CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms. Nucleic Acids Res. 2021;49:6213-6237 pubmed publisher
Malgundkar S, Burney I, Al Moundhri M, Al Kalbani M, Lakhtakia R, Okamoto A, et al. E2F5 Promotes the Malignancy of Ovarian Cancer Via the Regulation of Hippo and Wnt Pathways. Genet Test Mol Biomarkers. 2021;25:179-186 pubmed publisher
Malgundkar S, Burney I, Al Moundhri M, Al Kalbani M, Lakhtakia R, Okamoto A, et al. FAT4 silencing promotes epithelial-to-mesenchymal transition and invasion via regulation of YAP and β-catenin activity in ovarian cancer. BMC Cancer. 2020;20:374 pubmed publisher
Sim J, Jeong K. Monitoring Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells via Investigation of Mitochondrial Dysfunction. Methods Protoc. 2020;3: pubmed publisher
Funfak A, Bouzhir L, Gontran E, Minier N, Dupuis Williams P, Gobaa S. Biophysical Control of Bile Duct Epithelial Morphogenesis in Natural and Synthetic Scaffolds. Front Bioeng Biotechnol. 2019;7:417 pubmed publisher
Kao H, Kuo C, Chen K, Chen J. Preparation of Gelatin and Gelatin/Hyaluronic Acid Cryogel Scaffolds for the 3D Culture of Mesothelial Cells and Mesothelium Tissue Regeneration. Int J Mol Sci. 2019;20: pubmed publisher
Liu J, Ma ayeh S, Peirasmaki D, Lundström Stadelmann B, Hellman L, Svard S. Secreted Giardia intestinalis cysteine proteases disrupt intestinal epithelial cell junctional complexes and degrade chemokines. Virulence. 2018;9:879-894 pubmed publisher

product information

Product Type :

Antibody

Product Name :

E-cadherin Polyclonal Antibody

Catalog # :

PA5-32178

Quantity :

100 uL

Price :

US 558.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

Species :

Human, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

E-Cadherin (epithelial cadherin) is a classical cadherin from the cadherin (alcium dependent adhesion protein) superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. E-cadherin plays a central role in the growth and development of cells by controlling tissue architecture, and maintenance of tissue integrity. In humans, E-cadherin is encoded by the CDH1 gene present on chromosome 16. Studies have demonstrated that reduction and/or loss of E-cadherin expression in carcinomas correlates positively with the potential of these tumors for invasion and metastasis.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 338 and 649 of Human E-cadherin

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:10,000

Aliases :

AA960649; ARC-1; cadherin 1; cadherin 1, E-cadherin (epithelial); cadherin 1, epithelial; cadherin 1, type 1; cadherin 1, type 1, E-cadherin (epithelial); cadherin e; cadherin-1; cadherin-E; calcium-dependent adhesion protein, epithelial; CAM 120/80; CD324; CDH1; CDHE; cell adhesion molecule; cell-CAM 120/80; ECAD; E-cad; E-Cad/CTF1; E-Cad/CTF2; E-Cad/CTF3; Ecadherin; E-cadherin; E-cadherin 1; E-cadherin precursor; Epithelial cadherin; hab; half baked; LCAM; L-CAM; Um; UVO; Uvomorulin