RAD50 Polyclonal Antibody | Invitrogen PA5-32176 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RAD50 Polyclonal Antibody

catalog :

PA5-32176

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

Saccharomyces cerevisiae S288C

application :

western blot

citations: 4

Reference
Kissling V, Reginato G, Bianco E, Kasaciunaite K, Tilma J, Cereghetti G, et al. Mre11-Rad50 oligomerization promotes DNA double-strand break repair. Nat Commun. 2022;13:2374 pubmed publisher
Khayat F, Cannavo E, Alshmery M, Foster W, Chahwan C, Maddalena M, et al. Inhibition of MRN activity by a telomere protein motif. Nat Commun. 2021;12:3856 pubmed publisher
Marsella A, Gobbini E, Cassani C, Tisi R, Cannavo E, Reginato G, et al. Sae2 and Rif2 regulate MRX endonuclease activity at DNA double-strand breaks in opposite manners. Cell Rep. 2021;34:108906 pubmed publisher
Cannavo E, Johnson D, Andres S, Kissling V, Reinert J, Garcia V, et al. Regulatory control of DNA end resection by Sae2 phosphorylation. Nat Commun. 2018;9:4016 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RAD50 Polyclonal Antibody

Catalog # :

PA5-32176

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Yeast

Applications :

Western Blot: 1:500-1:3,000

Species :

Yeast

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Rad50-13B3 recognizes human Rad50, a 153a protein involved in DNA double strand break repair. Rad50 is associated with Mre11 and p95 (Nibrin) to form a multiprotein complex involved in the double strand break repair process. Upon DNA damage, Rad50 and Mre11 redistribute and are co-localized within the nucleus of damaged cells.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 644 and 989 of Yeast RAD50

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:3,000

Aliases :

153 kDa protein; DNA repair protein RAD50; hRad50; hsRAD50; I79_004319; mRad50; Mrell; MRX complex DNA-binding subunit; N0872; NBSLD; Rad50; RAD50 2; RAD50 double strand break repair protein; RAD50 homolog (S. cerevisiae); RAD50 homolog, double strand break repair protein; RAD50 PEN; RAD502; RAD50-2; RAD50-3; Rad50l; YNL250W