ZC3HAV1 Polyclonal Antibody | Invitrogen PA5-31650 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ZC3HAV1 Polyclonal Antibody

catalog :

PA5-31650

quantity :

100 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 5

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1b	Tang Q, Wang X, Gao G. The Short Form of the Zinc Finger Antiviral Protein Inhibits Influenza A Virus Protein Expression and Is Antagonized by the Virus-Encoded NS1. J Virol. 2017;91: pubmed publisher
	Sharp C, Thompson B, Nash T, Diebold O, Pinto R, Thorley L, et al. CpG dinucleotide enrichment in the influenza A virus genome as a live attenuated vaccine development strategy. PLoS Pathog. 2023;19:e1011357 pubmed publisher
	Xia T, Li X, Wang X, Zhu Y, Zhang H, Cheng W, et al. N(6)-methyladenosine-binding protein YTHDF1 suppresses EBV replication and promotes EBV RNA decay. EMBO Rep. 2021;22:e50128 pubmed publisher
	Lin Y, Chiweshe S, McCormick D, Raper A, Wickenhagen A, DeFillipis V, et al. Human cytomegalovirus evades ZAP detection by suppressing CpG dinucleotides in the major immediate early 1 gene. PLoS Pathog. 2020;16:e1008844 pubmed publisher
	Ying L, Cheng H, Xiong X, Yuan L, Peng Z, Wen Z, et al. Interferon alpha antagonizes the anti-hepatoma activity of the oncolytic virus M1 by stimulating anti-viral immunity. Oncotarget. 2017;8:24694-24705 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ZC3HAV1 Polyclonal Antibody

Catalog # :

PA5-31650

Quantity :

100 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:5,000-1:20,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 401 and 721 of Human ZC3HAV1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:5,000-1:20,000

Aliases :

1200014N16Rik; 2900058M19Rik; 9130009D18Rik; 9830115L13Rik; ADP-ribosyltransferase diphtheria toxin-like 13; ARTD13; CCCH-type zinc finger antiviral protein (Zap); D6Bwg1452e; FLB6421; Inactive Poly [ADP-ribose] polymerase 13; PARP13; PRO1677; rZAP; ZAP; ZC3H2; Zc3hav1; ZC3HDC2; zinc finger antiviral protein; Zinc finger CCCH domain-containing protein 2; zinc finger CCCH type, antiviral 1; zinc finger CCCH-type antiviral protein 1; zinc finger CCCH-type containing, antiviral 1; zinc finger CCCH-type, antiviral 1

more info or order :

Invitrogen product webpage