This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
C14orf130 Polyclonal Antibody
catalog :
PA5-31559
quantity :
100 uL
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 3
Reference
Isobe Y, Okumura M, McGregor L, Brittain S, Jones M, Liang X, et al. Manumycin polyketides act as molecular glues between UBR7 and P53. Nat Chem Biol. 2020;: pubmed publisher
Koyuncu S, Saez I, Lee H, Gutiérrez García R, Pokrzywa W, Fatima A, et al. The ubiquitin ligase UBR5 suppresses proteostasis collapse in pluripotent stem cells from Huntington's disease patients. Nat Commun. 2018;9:2886 pubmed publisher
Saez I, Koyuncu S, Gutiérrez García R, Dieterich C, Vilchez D. Insights into the ubiquitin-proteasome system of human embryonic stem cells. Sci Rep. 2018;8:4092 pubmed publisher
product information
Product Type :
Antibody
Product Name :
C14orf130 Polyclonal Antibody
Catalog # :
PA5-31559
Quantity :
100 uL
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human
Applications :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway, recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation.
Immunogen :
Recombinant fragment corresponding to a region within amino acids 105 and 425 of Human UBR7
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Aliases :
5730410I19Rik; AA589405; AW557761; C14orf130; C21H14ORF130; fb74a06; hypothetical protein LOC322815; LOW QUALITY PROTEIN: putative E3 ubiquitin-protein ligase UBR7; N-recognin-7; Putative E3 ubiquitin-protein ligase UBR7; RGD1359144; RING-type E3 ubiquitin transferase UBR7; ubiquitin protein ligase E3 component n-recognin 7; ubiquitin protein ligase E3 component n-recognin 7 (putative); Ubr7; wu:fb74a06; wu:fi29b06; zgc:55404
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA