TRAF3IP1 Polyclonal Antibody | Invitrogen PA5-30507 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRAF3IP1 Polyclonal Antibody

catalog :

PA5-30507

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Bosakova M, Abraham S, Nita A, Hruba E, Buchtová M, Taylor S, et al. Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling. EMBO Mol Med. 2020;12:e11739 pubmed publisher
Taylor S, Dantas T, Durán I, Wu S, Lachman R, Nelson S, et al. Mutations in DYNC2LI1 disrupt cilia function and cause short rib polydactyly syndrome. Nat Commun. 2015;6:7092 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRAF3IP1 Polyclonal Antibody

Catalog # :

PA5-30507

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Tumor necrosis factor receptor (TNFR) superfamily members transmit signals regulating proliferation, differentiation and apoptosis in various types of cells. TNFR-associated factors (TRAFs) are a family of proteins that were initially discovered as downstream signal transducers of the TNFR superfamily. TRAF3 contains an N-terminal ring finger/zinc finger region that is thought to be essential for downstream signaling. MIP-T3 is associated with TRAF3. MIP-T3 binds to taxol-stabilized microtubules and to tubulin in vitro, and MIP-T3 recruits TRAF3 to microtubules when both proteins are overexpressed. The MIP-T3/TRAF3 interaction requires the coiled-coil TRAF-N domain of TRAF3. This interaction may provide a novel mechanism in sequestering TRAF3 to the cytoskeletal network.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 1 and 223 of Human TRAF3IP1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

3930402D05Rik; AU041749; IFT54; interleukin 13 receptor alpha 1-binding protein-1; interleukin-13 receptor alpha 1-binding protein 1; Intraflagellar transport protein 54 homolog; microtubule interacting protein that associates with TRAF3; microtubule-interacting protein associated with TRAF3; microtubule-interacting protein that associates with TRAF3; MIPT3; MIP-T3; SLSN9; TNF receptor-associated factor 3 interacting protein 1; TRAF3 interacting protein 1; TRAF3-interacting protein 1; TRAF3IP1