ACSL6 Polyclonal Antibody | Invitrogen PA5-30465 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ACSL6 Polyclonal Antibody

catalog :

PA5-30465

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot

citations: 2

Reference
Cao Y, Vergnes L, Wang Y, Pan C, Chella Krishnan K, Moore T, et al. Sex differences in heart mitochondria regulate diastolic dysfunction. Nat Commun. 2022;13:3850 pubmed publisher
Stierwalt H, Ehrlicher S, Robinson M, Newsom S. Diet and Exercise Training Influence Skeletal Muscle Long-Chain acyl-CoA Synthetases. Med Sci Sports Exerc. 2020;52:569-576 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ACSL6 Polyclonal Antibody

Catalog # :

PA5-30465

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

FACL6 is involved in activation of long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. It plays an important role in fatty acid metabolism in brain and the acyl-CoAs produced may be utilized exclusively for the synthesis of the brain lipid. FACL6 is expressed predominantly in erythrocyte precursors, in particular in reticulocytes, fetal blood cells derieved from fetal liver, haemopoietic stem cells from cord blood, bone marrow, and brain. Expression is low at earlier stages of erythroid development but is very high in reticulocytes. This protein is involved in myelodysplastic syndrome (MDS) with basophilia, acute myelogenous leukemia (AML) with eosinophilia, and acute eosinophilic leukemia (AEL). It is characterized by a chromosomal translocation t(5;12)(q31;p13) that involves ETV6 and ACSL6.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 452 and 687 of Human ACSL6

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:3,000

Aliases :

A330035H04Rik; ACS2; ACSL6; acyl-CoA synthetase long-chain family member 6; Arachidonate--CoA ligase; AW050338; FACL6; fatty acid Coenzyme A ligase, long chain 6; fatty-acid-Coenzyme A ligase, long-chain 6; KIAA0837; L LACS5; LACS; LACS 6; LACS2; LACS5; Lacsl; long fatty acyl-CoA synthetase 2; long-chain acyl-CoA synthetase 6; Long-chain-fatty-acid--CoA ligase 6; long-chain-fatty-acid--CoA ligase, brain isozyme; mKIAA0837