ISG20 Polyclonal Antibody | Invitrogen PA5-30073 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ISG20 Polyclonal Antibody

catalog :

PA5-30073

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 4

Reference
Karlowitz R, Stanifer M, Roedig J, Andrieux G, Bojkova D, Bechtel M, et al. USP22 controls type III interferon signaling and SARS-CoV-2 infection through activation of STING. Cell Death Dis. 2022;13:684 pubmed publisher
Liu G, Lee J, Parker Z, Acharya D, Chiang J, van Gent M, et al. ISG15-dependent activation of the sensor MDA5 is antagonized by the SARS-CoV-2 papain-like protease to evade host innate immunity. Nat Microbiol. 2021;6:467-478 pubmed publisher
Liu G, Lee J, Parker Z, Acharya D, Chiang J, van Gent M, et al. ISG15-dependent Activation of the RNA Sensor MDA5 and its Antagonism by the SARS-CoV-2 papain-like protease. bioRxiv. 2020;: pubmed publisher
Feng J, Wickenhagen A, Turnbull M, Rezelj V, Kreher F, Tilston Lunel N, et al. Interferon-Stimulated Gene (ISG)-Expression Screening Reveals the Specific Antibunyaviral Activity of ISG20. J Virol. 2018;92: pubmed publisher

product information

Product Type :

Antibody

Product Name :

ISG20 Polyclonal Antibody

Catalog # :

PA5-30073

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Interferon-induced antiviral exoribonuclease that acts on single-stranded RNA and also has minor activity towards single-stranded DNA. Exhibits antiviral activity against RNA viruses including hepatitis C virus (HCV), hepatitis A virus (HAV) and yellow fever virus (YFV) in an exonuclease-dependent manner. May also play additional roles in the maturation of snRNAs and rRNAs, and in ribosome biogenesis. [UniProt]

Immunogen :

Recombinant fragment corresponding to a region within amino acids 1 and 181 of Human ISG20

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

1600023I01Rik; 2010107M23Rik; 20kDa; CD25; DnaQL; estrogen-regulated transcript 45 protein; HEM45; interferon stimulated exonuclease; interferon stimulated exonuclease 20; interferon stimulated exonuclease gene 20; interferon stimulated exonuclease gene 20kDa; interferon stimulated gene 20kDa; interferon-stimulated gene 20 kDa protein; interferon-stimulated protein; ISG20; Promyelocytic leukemia nuclear body-associated protein ISG20; Protein DnaQL