This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
Cytokeratin 8 Polyclonal Antibody
catalog :
PA5-29607
quantity :
100 uL
price :
US 538.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 3
Reference
Brown M, Abdollahi B, Wilkins O, Lu H, Chakraborty P, Ognjenovic N, et al. Phenotypic heterogeneity driven by plasticity of the intermediate EMT state governs disease progression and metastasis in breast cancer. Sci Adv. 2022;8:eabj8002 pubmed publisher
Ognjenovic N, Bagheri M, Mohamed G, Xu K, Chen Y, Mohamed Saleem M, et al. Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors. Dev Cell. 2020;55:544-557.e6 pubmed publisher
Pérez Sánchez J, Terova G, Simó Mirabet P, Rimoldi S, Folkedal O, Calduch Giner J, et al. Skin Mucus of Gilthead Sea Bream (Sparus aurata L.). Protein Mapping and Regulation in Chronically Stressed Fish. Front Physiol. 2017;8:34 pubmed publisher
product information
Product Type :
Antibody
Product Name :
Cytokeratin 8 Polyclonal Antibody
Catalog # :
PA5-29607
Quantity :
100 uL
Price :
US 538.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Cytokeratin 8 is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. Cutokeratin 8 typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis.
Immunogen :
Recombinant fragment corresponding to a region within amino acids 49 and 301 of Human Cytokeratin 8
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Aliases :
AA960620; AL022697; AU019895; CARD2; cb186; CK8; CK-8; CYK8; CYKER; cytokeratin 8; cytokeratin 8 (370 AA); cytokeratin endo A; Cytokeratin-8; cytokeratin-A; DreK8; EndoA; etID33550.23; etID43142.23; etID43142.8; K2C8; K8; KERA; keratin 8; keratin 8, type II; keratin complex 2, basic, gene 8; keratin, type 2, gene 8; Keratin, type II cytoskeletal 8; keratin, type II cytoskeletal 8-like protein; keratin-8; KO; Krt-2.8; Krt2-8; krt8; LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8; sb:cb186; type II cytokeratin A (no.8); type-II keratin Kb8; wu:fa20h05; wu:fa95h10; wu:fb96c06; zfk8; zf-K8
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA