Filamin A alpha-2 Polyclonal Antibody | Invitrogen PA5-29598 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Filamin A alpha-2 Polyclonal Antibody

catalog :

PA5-29598

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 4d	Pleines I, Woods J, Chappaz S, Kew V, Foad N, Ballester BeltrÃ¡n J, et al. Mutations in tropomyosin 4 underlie a rare form of human macrothrombocytopenia. J Clin Invest. 2017;127:814-829 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Filamin A alpha-2 Polyclonal Antibody

Catalog # :

PA5-29598

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 1769 and 2098 of Human Filamin A alpha 2

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

ABP-280; ABPX; actin binding protein 280; actin-binding protein 280; alpha filamin; alpha-filamin; CSBS; CVD1; dilated pupils 2; Dilp2; Endothelial actin-binding protein; Endothelial actin-binding protein 280); F730004A14Rik; filamin A; filamin A, alpha; filamin, alpha; filamin-1; Filamin-A; FLN; FLN1; FLNA; FLN-A; FMD; GENA 379; MNS; NHBP; Non-muscle filamin; OPD; OPD1; OPD2; RGD1560614; XLVD; XMVD

more info or order :

Invitrogen product webpage