RGS1 Polyclonal Antibody | Invitrogen PA5-29579 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

RGS1 Polyclonal Antibody

catalog :

PA5-29579

quantity :

100 uL

price :

US 481.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Reference
Sun M, Wang Y, Zhu J, Lv C, Wu K, Wang X, et al. Critical role for non‑GAP function of Gαs in RGS1‑mediated promotion of melanoma progression through AKT and ERK phosphorylation. Oncol Rep. 2018;39:2673-2680 pubmed publisher
Wostradowski T, Gudi V, Pul R, Gingele S, Lindquist J, Stangel M, et al. Effect of interferon-Î²1b on CXCR4-dependent chemotaxis in T cells from multiple sclerosis patients. Clin Exp Immunol. 2015;182:162-72 pubmed publisher

product information

Product Type :

Antibody

Product Name :

RGS1 Polyclonal Antibody

Catalog # :

PA5-29579

Quantity :

100 uL

Price :

US 481.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a member of the regulator of G-protein signaling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 1 and 209 of Human RGS1

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

1R20; B-cell activation protein BL34; BL34; Early response protein 1R20; epididymis secretory protein Li 87; HEL-S-87; IER1; immediate-early response 1, B-cell specific; IR20; Regulator of G-protein signaling 1; regulator of G-protein signalling 1; RGS1