G3BP1 Polyclonal Antibody | Invitrogen PA5-29455 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

G3BP1 Polyclonal Antibody

catalog :

PA5-29455

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunocytochemistry knockout validation

more info or order :

Invitrogen product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry knockout validation; human; 1:500; loading ...; fig s3d	Guillén Boixet J, Kopach A, Holehouse A, Wittmann S, Jahnel M, Schlüßler R, et al. RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell. 2020;181:346-361.e17 pubmed publisher
immunocytochemistry; human; loading ...; fig s3a	Matějů D, Franzmann T, Patel A, Kopach A, Boczek E, Maharana S, et al. An aberrant phase transition of stress granules triggered by misfolded protein and prevented by chaperone function. EMBO J. 2017;36:1669-1687 pubmed publisher
	Xu S, Gierisch M, Schellhaus A, Poser I, Alberti S, Salomons F, et al. Cytosolic stress granules relieve the ubiquitin-proteasome system in the nuclear compartment. EMBO J. 2023;42:e111802 pubmed publisher
	Giovannucci T, Salomons F, Stoy H, Herzog L, Xu S, Qian W, et al. Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy. Autophagy. 2022;18:1486-1502 pubmed publisher
	Chang D, Luong P, Li Q, LeBarron J, Anderson M, Barrett L, et al. Small-molecule modulators of INAVA cytosolic condensate and cell-cell junction assemblies. J Cell Biol. 2021;220: pubmed publisher
	Yang M, Gallo Ebert C, Hayward M, Liu W, McDonough V, Nickels J. Human Insulin Growth Factor 2 mRNA Binding Protein 2 Increases MicroRNA 33a/b Inhibition of Liver ABCA1 Expression and Alters Low-Density Apolipoprotein Levels in Mice. Mol Cell Biol. 2020;40: pubmed publisher
	McGurk L, Rifai O, Bonini N. TDP-43, a protein central to amyotrophic lateral sclerosis, is destabilized by tankyrase-1 and -2. J Cell Sci. 2020;133: pubmed publisher

product information

Product Type :

Antibody

Product Name :

G3BP1 Polyclonal Antibody

Catalog # :

PA5-29455

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes one of the DNA-unwinding enzymes which prefers partially unwound 3'-tailed substrates and can also unwind partial RNA/DNA and RNA/RNA duplexes in an ATP-dependent fashion. This enzyme is a member of the heterogeneous nuclear RNA-binding proteins and is also an element of the Ras signal transduction pathway. It binds specifically to the Ras-GTPase-activating protein by associating with its SH3 domain. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.

Immunogen :

Recombinant protein fragment corresponding to a region within amino acids 147 and 466 of Human G3BP1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:1,000-1:10,000

Aliases :

AI849976; ATP-dependent DNA helicase VIII; B430204O07; C87777; DNA helicase VIII; G3BP; G3BP stress granule assembly factor 1; G3bp1; G3BP-1; GAP binding protein; GAP SH3 binding protein; GAP SH3 domain-binding protein 1; GTPase activating protein (SH3 domain) binding protein 1; hDH VIII; HDH-VIII; MGC111040; mKIAA4115; Ras GTPase-activating protein-binding protein 1; RasGAP-associated endoribonuclease G3BP; Ras-GTPase-activating protein SH3-domain binding protein 1; Ras-GTPase-activating protein SH3-domain-binding protein; RGD1310666

more info or order :

Invitrogen product webpage