TUBA1A Polyclonal Antibody | Invitrogen PA5-29444 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TUBA1A Polyclonal Antibody

catalog :

PA5-29444

quantity :

100 uL

price :

US 478.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, chicken

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 14

Reference
Deng K, Lu Y, Finnema S, Vangjeli K, Huang J, Huang L, et al. Application of In vitro transcytosis models to brain targeted biologics. PLoS ONE. 2023;18:e0289970 pubmed publisher
Riva M, Moriceau S, Morabito A, Dossi E, Sanchez Bellot C, Azzam P, et al. Aberrant survival of hippocampal Cajal-Retzius cells leads to memory deficits, gamma rhythmopathies and susceptibility to seizures in adult mice. Nat Commun. 2023;14:1531 pubmed publisher
Singh A, Busacca S, Gaba A, Sheaff M, Poile C, Nakas A, et al. BAP1 loss induces mitotic defects in mesothelioma cells through BRCA1-dependent and independent mechanisms. Oncogene. 2022;: pubmed publisher
Yunes S, Willoughby J, Kwan J, Biagi J, Pokharel N, Chin H, et al. Factor quinolinone inhibitors disrupt spindles and multiple LSF (TFCP2)-protein interactions in mitosis, including with microtubule-associated proteins. PLoS ONE. 2022;17:e0268857 pubmed publisher
Stoiber P, Scribani Rossi P, Pokharel N, Germany J, York E, Schaus S, et al. Factor quinolinone inhibitors alter cell morphology and motility by destabilizing interphase microtubules. Sci Rep. 2021;11:23564 pubmed publisher
Sakowicz A, Bralewska M, Pietrucha T, Figueras F, Habrowska G xf3 rczy x144 ska D, Piastowska Ciesielska A, et al. The Preeclamptic Environment Promotes the Activation of Transcription Factor Kappa B by P53/RSK1 Complex in a HTR8/SVneo Trophoblastic Cell Line. Int J Mol Sci. 2021;22: pubmed publisher
Kim H, Lee J, Kim S, Lee S, Jung D, Williams D. Investigation of niclosamide as a repurposing agent for skeletal muscle atrophy. PLoS ONE. 2021;16:e0252135 pubmed publisher
Lee J, Kim S, Kim J, Kim H, Um J, Jung D, et al. Lithium Chloride Protects against Sepsis-Induced Skeletal Muscle Atrophy and Cancer Cachexia. Cells. 2021;10: pubmed publisher
Selyutina A, Diaz Griffero F. Biochemical detection of capsid in the nucleus during HIV-1 infection. STAR Protoc. 2021;2:100323 pubmed publisher
Selyutina A, Persaud M, Lee K, KEWALRAMANI V, Diaz Griffero F. Nuclear Import of the HIV-1 Core Precedes Reverse Transcription and Uncoating. Cell Rep. 2020;32:108201 pubmed publisher
Kostrzewska Poczekaj M, Bednarek K, Jarmuz Szymczak M, Bodnar M, Filas V, Marszalek A, et al. Copy number gains of the putative CRKL oncogene in laryngeal squamous cell carcinoma result in strong nuclear expression of the protein and influence cell proliferation and migration. Sci Rep. 2020;10:24 pubmed publisher
Piekarowicz K, Bertrand A, Azibani F, Beuvin M, Julien L, Machowska M, et al. A Muscle Hybrid Promoter as a Novel Tool for Gene Therapy. Mol Ther Methods Clin Dev. 2019;15:157-169 pubmed publisher
Lukacs M, Gilley J, Zhu Y, Orsomando G, Angeletti C, Liu J, et al. Severe biallelic loss-of-function mutations in nicotinamide mononucleotide adenylyltransferase 2 (NMNAT2) in two fetuses with fetal akinesia deformation sequence. Exp Neurol. 2019;320:112961 pubmed publisher
Dubińska Magiera M, Kozioł K, Machowska M, Piekarowicz K, Filipczak D, Rzepecki R. Emerin Is Required for Proper Nucleus Reassembly after Mitosis: Implications for New Pathogenetic Mechanisms for Laminopathies Detected in EDMD1 Patients. Cells. 2019;8: pubmed publisher

product information

Product Type :

Antibody

Product Name :

TUBA1A Polyclonal Antibody

Catalog # :

PA5-29444

Quantity :

100 uL

Price :

US 478.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Chicken, Drosophila, Human, Insect, Mouse, Non-human primate, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:20,000

Species :

Chicken, Drosophila, Human, Insect, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Alpha Tubulin is a part of a heterodimer consisting of alpha and beta tubulin subunits. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha-beta tubulin heterodimer is the basic building block of microtubules, and this intracellular cylindrical filamentous structure is present in almost eukaryotic cells. Microtubules serve as structural supports and lines of transport within the cell, as well as serving a key role in mitosis. Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. The gene that encodes alpha tubulin is highly similar to the mouse and rat Tuba1 gene. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells.

Immunogen :

Recombinant protein encompassing a sequence within the center region of human alpha Tubulin. The exact sequence is proprietary.

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Frozen): Assay-dependent, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:20,000

Aliases :

alpha 1a antibody; alpha 3 antibody; alpha-tubulin; alpha-tubulin 1; Alpha-tubulin 3; alpha-tubulin 3 antibody; Alpha-tubulin isotype M-alpha-1; B-ALPHA-1; B-ALPHA-1 antibody; brain-specific antibody; Detyrosinated tubulin alpha-1A chain; FLJ25113 antibody; FLJ30169; H2 ALPHA; H2ALPHA; H2-ALPHA; hum-a-tub1; hum-a-tub1 antibody; hum-a-tub2; hum-a-tub2 antibody; LIS3; LIS3 antibody; LOC106557476; M40; MGC117247; MGC16435; OK/SW cl.56; OK/SWcl.56; OK/SW-cl.56; Talpha1 alpha-tubulin; TUBA1; Tuba-1; Tuba1a; TUBA1A antibody; TUBA3; TUBA3 antibody; TUBA6; TUBB1; TUBB5; tubulin alpha 1a; tubulin alpha-1 chain; Tubulin alpha-1A chain; tubulin alpha-1A chain antibody; tubulin alpha-3 chain; tubulin alpha-3 chain antibody; Tubulin B-alpha-1; tubulin B-alpha-1 antibody; tubulin, alpha 1; tubulin, alpha 1 (testis specific); tubulin, alpha 1A; tubulin, alpha 6; tubulin, alpha, brain-specific; unnamed protein product