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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ALDH1A3 Polyclonal Antibody
catalog :
PA5-29188
quantity :
100 uL
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; 1:1000; loading ...; fig 5
Bhat K, Sandler K, Duhachek Muggy S, Alli C, Cheng F, Moatamed N, et al. Serum erythropoietin levels, breast cancer and breast cancer-initiating cells. Breast Cancer Res. 2019;21:17 pubmed publisher
Fau xdf J, Sprang B, Leukel P, Sommer C, Nikolova T, Ringel F, et al. ALDH1A3 Segregated Expression and Nucleus-Associated Proteasomal Degradation Are Common Traits of Glioblastoma Stem Cells. Biomedicines. 2021;10: pubmed publisher
Zirjacks L, Stransky N, Klumpp L, Prause L, Eckert F, Zips D, et al. Repurposing Disulfiram for Targeting of Glioblastoma Stem Cells: An In Vitro Study. Biomolecules. 2021;11: pubmed publisher
Nozaki Y, Motomura H, Tamori S, Kimura Y, Onaga C, Kanai S, et al. High PKCĪ» expression is required for ALDH1-positive cancer stem cell function and indicates a poor clinical outcome in late-stage breast cancer patients. PLoS ONE. 2020;15:e0235747 pubmed publisher
Lu T, Bankhead A, Ljungman M, Neamati N. Multi-omics profiling reveals key signaling pathways in ovarian cancer controlled by STAT3. Theranostics. 2019;9:5478-5496 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ALDH1A3 Polyclonal Antibody
Catalog # :
PA5-29188
Quantity :
100 uL
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse, Rat
Applications :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Species :
Human, Mouse, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
ALDH1A3 are aldehyde dehydrogenase isozymes which are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. The enzyme encoded by the ALDH1A3 gene uses retinal as a substrate, either in a free or cellular retinol-binding protein form.
Immunogen :
Recombinant fragment corresponding to a region within amino acids 126 and 423 of Human ALDH1A3
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Aliases :
acetaldehyde dehydrogenase 6; aldehyde dehydrogenase 1 family member A3; aldehyde dehydrogenase 1 family, member A3; aldehyde dehydrogenase 6; Aldehyde dehydrogenase family 1 member A3; aldehyde dehydrogenase family 1, subfamily A3; aldehyde dehydrogenase-6; ALDH1A3; ALDH1A6; ALDH6; ALDHA1A3; MCOP8; ralDH3; RALDH-3; Retinaldehyde dehydrogenase 3; V1
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA