NPR1 Polyclonal Antibody | Invitrogen PA5-29049 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

NPR1 Polyclonal Antibody

catalog :

PA5-29049

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, rat, domestic rabbit

application :

western blot

citations: 7

Reference
Suzuki J, Kaji K, Nishimura N, Kubo T, Tomooka F, Shibamoto A, et al. A Combination of an Angiotensin II Receptor and a Neprilysin Inhibitor Attenuates Liver Fibrosis by Preventing Hepatic Stellate Cell Activation. Biomedicines. 2023;11: pubmed publisher
Zhang X, Zhou K, Tian K, Zhu Q, Liu W, Liu Z, et al. VDR Regulates BNP Promoting Neurite Growth and Survival of Cochlear Spiral Ganglion Neurons through cGMP-PKG Signaling Pathway. Cells. 2022;11: pubmed publisher
Sun F, Zhou K, Tian K, Zhang X, Liu W, Wang J, et al. Atrial Natriuretic Peptide Promotes Neurite Outgrowth and Survival of Cochlear Spiral Ganglion Neurons in vitro Through NPR-A/cGMP/PKG Signaling. Front Cell Dev Biol. 2021;9:681421 pubmed publisher
Mezzasoma L, Talesa V, Costanzi E, Bellezza I. Natriuretic Peptides Regulate Prostate Cells Inflammatory Behavior: Potential Novel Anticancer Agents for Prostate Cancer. Biomolecules. 2021;11: pubmed publisher
Mezzasoma L, Talesa V, Romani R, Bellezza I. ANP and BNP Exert Anti-Inflammatory Action via NPR-1/cGMP Axis by Interfering with Canonical, Non-Canonical, and Alternative Routes of Inflammasome Activation in Human THP1 Cells. Int J Mol Sci. 2020;22: pubmed publisher
Sun F, Zhou K, Tian K, Wang J, Qiu J, Zha D. Atrial Natriuretic Peptide Improves Neurite Outgrowth from Spiral Ganglion Neurons In Vitro through a cGMP-Dependent Manner. Neural Plast. 2020;2020:8831735 pubmed publisher
Mao Y, Han S, Zhang S, Zhang Z, Kong C, Chen H, et al. An approach using Caenorhabditis elegans screening novel targets to suppress tumour cell proliferation. Cell Prolif. 2020;53:e12832 pubmed publisher

product information

Product Type :

Antibody

Product Name :

NPR1 Polyclonal Antibody

Catalog # :

PA5-29049

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Rabbit, Rat

Applications :

Western Blot: 1:500-1:3,000

Species :

Human, Rabbit, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Guanylyl cyclases, catalyzing the production of cGMP from GTP, are classified as soluble and membrane forms. The membrane guanylyl cyclases, often termed guanylyl cyclases A through F, form a family of cell-surface receptors with a similar topographic structure: an extracellular ligand-binding domain, a single membrane-spanning domain, and an intracellular region that contains a protein kinase-like domain and a cyclase catalytic domain. GC-A and GC-B function as receptors for natriuretic peptides; they are also referred to as atrial natriuretic peptide receptor A and type B. Also see NPR3, which encodes a protein with only the ligand-binding transmembrane and 37-amino acid cytoplasmic domains. NPR1 is a membrane-bound guanylate cyclase that serves as the receptor for both atrial and brain natriuretic peptides and BNP, respectively).

Immunogen :

Recombinant fragment corresponding to a region within amino acids 640 and 916 of Human NPR-A

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:3,000

Aliases :

AI893888; ANPa; ANP-A; ANPRA; ANPR-A; atrial natriuretic peptide A-type receptor; atrial natriuretic peptide receptor 1; atrial natriuretic peptide receptor A; atrial natriuretic peptide receptor type A; atrionatriuretic peptide receptor A; Gca; GC-A; Guanylate cyclase A; guanylyl cyclase-A; GUC2A; GUCY2A; natriuretic peptide A type receptor; natriuretic peptide receptor 1; natriuretic peptide receptor A; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A); Nppa receptor; Npr1; Npra; NPR-A; Pndr; testicular tissue protein Li 20