HES1 Polyclonal Antibody | Invitrogen PA5-28802 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HES1 Polyclonal Antibody

catalog :

PA5-28802

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 8

Reference
Singh A, Shuaib M, Prajapati K, Kumar S. Rutin Potentially Binds the Gamma Secretase Catalytic Site, Down Regulates the Notch Signaling Pathway and Reduces Sphere Formation in Colonospheres. Metabolites. 2022;12: pubmed publisher
Xu Y, Jiang S, Hu Y, Zhang Q, Su W. TGF-β3 induces lactate production in Sertoli cell through inhibiting the Notch pathway. Andrology. 2022;10:1644-1659 pubmed publisher
Islam S, Qassem K, Islam S, Parag R, Rahman M, Farhat W, et al. Genetic alterations of Keap1 confers chemotherapeutic resistance through functional activation of Nrf2 and Notch pathway in head and neck squamous cell carcinoma. Cell Death Dis. 2022;13:696 pubmed publisher
O Brien B, Mokry R, Schumacher M, Pulakanti K, Rao S, Terhune S, et al. Downregulation of neurodevelopmental gene expression in iPSC-derived cerebral organoids upon infection by human cytomegalovirus. iScience. 2022;25:104098 pubmed publisher
Minguzzi M, Panichi V, D Adamo S, Cetrullo S, Cattini L, Flamigni F, et al. Pleiotropic Roles of NOTCH1 Signaling in the Loss of Maturational Arrest of Human Osteoarthritic Chondrocytes. Int J Mol Sci. 2021;22: pubmed publisher
Kaminska A, Marek S, Pardyak L, Brzoskwinia M, Bilinska B, Hejmej A. Crosstalk between Androgen-ZIP9 Signaling and Notch Pathway in Rodent Sertoli Cells. Int J Mol Sci. 2020;21: pubmed publisher
Lv X, Chen X, Wang Y, Yu S, Pang L, Huang C. Aberrant expression of semaphorin 6B affects cell phenotypes in thyroid carcinoma by activating the Notch signalling pathway. Endokrynol Pol. 2021;72:29-36 pubmed publisher
Kaminska A, Marek S, Pardyak L, Brzoskwinia M, Pawlicki P, Bilinska B, et al. Disruption of androgen signaling during puberty affects Notch pathway in rat seminiferous epithelium. Reprod Biol Endocrinol. 2020;18:30 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HES1 Polyclonal Antibody

Catalog # :

PA5-28802

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:2,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.

Immunogen :

Synthetic peptide corresponding to a region within amino acids 1 and 45 of Human HES1

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:2,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Aliases :

BHLHB39; class B basic helix-loop-helix protein 39; FLJ20408; Hairy and enhancer of split 1; hairy and enhancer of split 1 (Drosophila); hairy and enhancer of split 1,; hairy homolog; Hairy-like; Hairy-like protein; hes family bHLH transcription factor 1; HES1; Hes-1; hHL; HL; HRY; RHL; transcription factor HES-1