GLI3 Polyclonal Antibody | Invitrogen PA5-28029 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

GLI3 Polyclonal Antibody

catalog :

PA5-28029

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, western blot knockout validation

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:2000; fig 4b	Kim K, Kabra A, Kim D, Xue Y, Huang Y, Hou P, et al. KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer. Sci Adv. 2022;8:eabl4618 pubmed publisher
	Duong T, Araujo Rincon M, Myneni N, Burleson M. Genetic alterations in MED12 promote castration-resistant prostate cancer through modulation of GLI3 signaling. Mol Biol Res Commun. 2023;12:63-70 pubmed publisher
	Lim G, Albrecht T, Piske M, Sarai K, Lee J, Ramshaw H, et al. 14-3-3ζ coordinates adipogenesis of visceral fat. Nat Commun. 2015;6:7671 pubmed publisher

product information

Product Type :

Antibody

Product Name :

GLI3 Polyclonal Antibody

Catalog # :

PA5-28029

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

This gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 243 and 773 of Human GLI3

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

ACLS; add; AI854843; anterior digit pattern deformity; AU023367; Bph; brachyphalangy; extra toes; GCPS; GLI family zinc finger 3; GLI family zinc finger 3 L homeolog; gli3; GLI3 C-terminally truncated form; GLI3 form of 190 kDa; GLI3 form of 83 kDa; GLI3 full length protein; GLI3 full-length protein; gli3.L; GLI3-190; GLI3-83; GLI3FL; GLI-Kruppel family member 3; GLI-Kruppel family member GLI3; GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome); glioma-associated oncogene family zinc finger 3; im:7142603; neural specific DNA binding protein; neural-specific DNA-binding protein xGLI3; oncogene GLI3; PAPA; PAP-A; PAPA1; PAPB; Pdn; PHS; polydactyly Nagoya; PPDIV; Transcriptional activator GLI3; Transcriptional repressor GLI3R; XELAEV_18031191mg; xgli3; xGLI-3; Xt; Zinc finger protein GLI3; zinc finger protein GLI3; transcriptional activator GLI3; zinc finger transcription factor Gli3

more info or order :

Invitrogen product webpage