P2X7 Polyclonal Antibody | Invitrogen PA5-28020 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

P2X7 Polyclonal Antibody

catalog :

PA5-28020

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:900; fig 4d	Giannuzzo A, Saccomano M, Napp J, Ellegaard M, Alves F, Novak I. Targeting of the P2X7 receptor in pancreatic cancer and stellate cells. Int J Cancer. 2016;139:2540-52 pubmed publisher
	Barrera Avalos C, Briceño P, Valdés D, Imarai M, Leiva Salcedo E, Rojo L, et al. P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells. iScience. 2021;24:103520 pubmed publisher
	Dunton C, Purves J, Hughes F, Jin H, Nagatomi J. Elevated hydrostatic pressure stimulates ATP release which mediates activation of the NLRP3 inflammasome via P2X4 in rat urothelial cells. Int Urol Nephrol. 2018;50:1607-1617 pubmed publisher

product information

Product Type :

Antibody

Product Name :

P2X7 Polyclonal Antibody

Catalog # :

PA5-28020

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse, Rat

Applications :

Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000

Species :

Human, Mouse, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay criteria.

Immunogen :

Recombinant protein fragment corresponding to a region within amino acids 103 and 348 of Human P2X7

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000

Aliases :

AI467586; ATP receptor; MGC20089; P2rx7; P2X purinoceptor 7; p2X receptor 7; P2X(7); P2X7; P2X7 purinoceptor; P2X7 receptor; P2X7R; P2Z; P2Z receptor; Purinergic receptor; purinergic receptor P2X 7; purinergic receptor P2X, ligand gated ion channel, 7; purinergic receptor P2X, ligand-gated ion channel, 7; purinergic receptor P2X7; purinergic receptor P2X7 variant A

more info or order :

Invitrogen product webpage