PLS3 Polyclonal Antibody | Invitrogen PA5-27883 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

PLS3 Polyclonal Antibody

catalog :

PA5-27883

quantity :

100 uL

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 6

Reference
Morandell J, Schwarz L, Basilico B, Tasciyan S, Dimchev G, Nicolas A, et al. Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021;12:3058 pubmed publisher
Garbett D, Bisaria A, Yang C, McCarthy D, Hayer A, Moerner W, et al. T-Plastin reinforces membrane protrusions to bridge matrix gaps during cell migration. Nat Commun. 2020;11:4818 pubmed publisher
Velthaus A, Cornils K, Hennigs J, Grüb S, Stamm H, Wicklein D, et al. The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia. Cancers (Basel). 2019;11: pubmed publisher
Lin S, Huang C, Gunda V, Sun J, Chellappan S, Li Z, et al. Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments. Cell Rep. 2019;28:2824-2836.e8 pubmed publisher
Alrafiah A. Evaluation of the role of an antioxidant gene in NSC-34 motor neuron-like cells as a model of a motor neuron disease. Folia Morphol (Warsz). 2018;: pubmed publisher
Sugimachi K, Gorges T, Bartkowiak K, Yokobori T, MÃ¼ller V, Shinden Y, et al. Circulating tumour cell-derived plastin3 is a novel marker for predicting long-term prognosis in patients with breast cancer. Br J Cancer. 2015;112:1519-26 pubmed publisher

product information

Product Type :

Antibody

Product Name :

PLS3 Polyclonal Antibody

Catalog # :

PA5-27883

Quantity :

100 uL

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:10,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Phospholipid scramblases (PLS) translocate phospholipids bidirectionally between inner and outer leaflets of the plasma membrane and are implicated in apoptosis (1,2). Members of this family, PLS1 and PLS3 are both substrates of Protein kinase C (PKC) delta and are phosphorylated by PKC-delta during apoptosis. PKC-delta translocates to mitochondria during apoptosis and phosphorylates PLS3. Overexpression of PLS3 in the HEK293 cells enhanced apoptosis induced by UV-irradiation.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 66 and 371 of Human T-Plastin

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:10,000

Aliases :

AI115446; AL024105; BMND18; LOW QUALITY PROTEIN: plastin-3; MGC128570 protein; plastin 3; plastin 3 (T isoform); plastin 3 (T-isoform); plastin 3, T; plastin-3; PLS3; T fimbrin; T plastin; T-fimbrin; T-plastin