Nrf2 Polyclonal Antibody | Invitrogen PA5-27882 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Nrf2 Polyclonal Antibody

catalog :

PA5-27882

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, zebrafish

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

citations: 27

Reference
Zhou Y, Wang Y, Wu X, Wu J, Yan J, Su W. Carthamin yellow attenuates brain injury in a neonatal rat model of ischemic-hypoxic encephalopathy by inhibiting neuronal ferroptosis in the hippocampus. Transl Neurosci. 2023;14:20220331 pubmed publisher
Luo C, Hou C, Yang D, Tan T, Chao C. Urolithin C alleviates pancreatic β-cell dysfunction in type 1 diabetes by activating Nrf2 signaling. Nutr Diabetes. 2023;13:24 pubmed publisher
Etemadi Y, Akakpo J, Ramachandran A, Jaeschke H. Nrf2 as a therapeutic target in acetaminophen hepatotoxicity: A case study with sulforaphane. J Biochem Mol Toxicol. 2023;37:e23505 pubmed publisher
Skiteva O, Yao N, Mantas I, Zhang X, Perlmann T, Svenningsson P, et al. Aberrant somatic calcium channel function in cNurr1 and LRRK2-G2019S mice. NPJ Parkinsons Dis. 2023;9:56 pubmed publisher
Wang P, Yi T, Mao S, Li M. Neuroprotective mechanism of human umbilical cord mesenchymal stem cell-derived extracellular vesicles improving the phenotype polarization of microglia via the PI3K/AKT/Nrf2 pathway in vascular dementia. Synapse. 2023;77:e22268 pubmed publisher
McClendon L, Garcia R, Lazaro T, Robledo A, Vasandani V, Luna Z, et al. A steroid receptor coactivator small molecule "stimulator" attenuates post-stroke ischemic brain injury. Front Mol Neurosci. 2022;15:1055295 pubmed publisher
Seo H, Lee S, Han E, Hwang J, Han S, Kim M, et al. Evogliptin Directly Inhibits Inflammatory and Fibrotic Signaling in Isolated Liver Cells. Int J Mol Sci. 2022;23: pubmed publisher
Su Y, Xu J, Chen S, Feng J, Li J, Lei Z, et al. Astragaloside IV protects against ischemia/reperfusion (I/R)-induced kidney injury based on the Keap1-Nrf2/ARE signaling pathway. Transl Androl Urol. 2022;11:1177-1188 pubmed publisher
Cuzziol C, Marzochi L, Possebon V, Kawasaki Oyama R, Mattos M, Junior V, et al. Regulation of VEGFA, KRAS, and NFE2L2 Oncogenes by MicroRNAs in Head and Neck Cancer. Int J Mol Sci. 2022;23: pubmed publisher
Long X, Wu H, Zhou Y, Wan Y, Kan X, Gong J, et al. Preventive Effect of Limosilactobacillus fermentum SCHY34 on Lead Acetate-Induced Neurological Damage in SD Rats. Front Nutr. 2022;9:852012 pubmed publisher
Liang M, Wang L, Sun Z, Chen X, Wang H, Qin L, et al. E3 ligase TRIM15 facilitates non-small cell lung cancer progression through mediating Keap1-Nrf2 signaling pathway. Cell Commun Signal. 2022;20:62 pubmed publisher
Han G, Cao C, Yang X, Zhao G, Hu X, Yu D, et al. Nrf2 expands the intracellular pool of the chaperone AHSP in a cellular model of β-thalassemia. Redox Biol. 2022;50:102239 pubmed publisher
D x105 browska K, Skowro x144 ska K, Popek M, Albrecht J, Zieli x144 ska M. The Role of Nrf2 Transcription Factor and Sp1-Nrf2 Protein Complex in Glutamine Transporter SN1 Regulation in Mouse Cortical Astrocytes Exposed to Ammonia. Int J Mol Sci. 2021;22: pubmed publisher
An J, Cheng L, Yang L, Song N, Zhang J, Ma K, et al. P- Hydroxybenzyl Alcohol Alleviates Oxidative Stress in a Nonalcoholic Fatty Liver Disease Larval Zebrafish Model and a BRL-3A Hepatocyte Via the Nrf2 Pathway. Front Pharmacol. 2021;12:646239 pubmed publisher
Sohn E, Kim Y, Kim J, Jeong S. Ficus erecta Thunb Leaves Alleviate Memory Loss Induced by Scopolamine in Mice via Regulation of Oxidative Stress and Cholinergic System. Mol Neurobiol. 2021;58:3665-3676 pubmed publisher
Eassawy M, Salem A, Ismail A. Biochemical study on the protective effect of curcumin on acetaminophen and gamma-irradiation induced hepatic toxicity in rats. Environ Toxicol. 2020;: pubmed publisher
Wang B, Kulikowicz E, Lee J, Koehler R, Yang Z. Sulforaphane Protects Piglet Brains from Neonatal Hypoxic-Ischemic Injury. Dev Neurosci. 2020;42:124-134 pubmed publisher
Hwang J, Kim W, Cho Y, Ryu J, Choi J, Jeong S, et al. Chloroquine reverses chemoresistance via upregulation of p21WAF1/CIP1 and autophagy inhibition in ovarian cancer. Cell Death Dis. 2020;11:1034 pubmed publisher
Stuchi L, Castanhole Nunes M, Maniezzo Stuchi N, Biselli Chicote P, Henrique T, Padovani Neto J, et al. VEGFA and NFE2L2 Gene Expression and Regulation by MicroRNAs in Thyroid Papillary Cancer and Colloid Goiter. Genes (Basel). 2020;11: pubmed publisher
Rahtes A, Li L. Polarization of Low-Grade Inflammatory Monocytes Through TRAM-Mediated Up-Regulation of Keap1 by Super-Low Dose Endotoxin. Front Immunol. 2020;11:1478 pubmed publisher
Nwakiban A, Cicolari S, Piazza S, Gelmini F, Sangiovanni E, Martinelli G, et al. Oxidative Stress Modulation by Cameroonian Spice Extracts in HepG2 Cells: Involvement of Nrf2 and Improvement of Glucose Uptake. Metabolites. 2020;10: pubmed publisher
Carrasco Wong I, Hernandez C, Jara Gutierrez C, Porras O, Casanello P. Human umbilical artery endothelial cells from Large-for-Gestational-Age newborn have increased antioxidant efficiency and gene expression. J Cell Physiol. 2019;234:18571-18586 pubmed publisher
Mitamura Y, Murai M, Mitoma C, Furue M. NRF2 Activation Inhibits Both TGF-β1- and IL-13-Mediated Periostin Expression in Fibroblasts: Benefit of Cinnamaldehyde for Antifibrotic Treatment. Oxid Med Cell Longev. 2018;2018:2475047 pubmed publisher
Mazur Bialy A, Kozlowska K, Pochec E, Bilski J, Brzozowski T. Myokine irisin-induced protection against oxidative stress in vitro. Involvement of heme oxygenase-1 and antioxidazing enzymes superoxide dismutase-2 and glutathione peroxidase. J Physiol Pharmacol. 2018;69:117-125 pubmed publisher
Akhtar F, Rouse C, Catano G, Montalvo M, Ullevig S, Asmis R, et al. Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress. J Neuroinflammation. 2017;14:195 pubmed publisher
Mukhopadhyay D, Priya P, Chattopadhyay A. Sodium fluoride affects zebrafish behaviour and alters mRNA expressions of biomarker genes in the brain: Role of Nrf2/Keap1. Environ Toxicol Pharmacol. 2015;40:352-9 pubmed publisher
Yang S, Yang X, Cao G. Acetyl-l-carnitine prevents homocysteine-induced suppression of Nrf2/Keap1 mediated antioxidation in human lens epithelial cells. Mol Med Rep. 2015;12:1145-50 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Nrf2 Polyclonal Antibody

Catalog # :

PA5-27882

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Avian, Human, Mouse, Plant, Rat, Reptile, Zebrafish

Applications :

ChIP Assay: 5 ug, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Species :

Avian, Human, Mouse, Plant, Rat, Reptile, Zebrafish

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Nfr1 (also designated TCF11), Nrf2 and Nfr3 are bZIP transcription factors that heterodimer with Maf proteins to bind MARE (Maf recognition elements) sequences. Nrf2 is widely expressed and is thought to translocate to the nucleus after treatment with xenobiotics and antioxidants, which stimulate its release from a repressor protein Keap1.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 108 and 413 of Human NRF2

Format :

Liquid

Applications w/Dilutions :

ChIP Assay: 5 ug, Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Immunoprecipitation: 1:100-1:500, Western Blot: 1:500-1:3,000

Aliases :

AI194320; E4TF1-60; E4TF1A; HEBP1; Nfe2l2; NF-E2-related factor 2; NFE2-related factor 2; NF-E2-related factor-2; NFT2; NRF2; NRF2A; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid 2-like 2; nuclear factor erythroid 2-related factor 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid 2 like 2; nuclear factor, erythroid 2-like 2; nuclear factor, erythroid derived 2, like 2; Unknown (protein for IMAGE:7945830)