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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
SERPINH1 Polyclonal Antibody
catalog :
PA5-27832
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
citations: 4
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 3a
Ji X, Chen Y, Ye G, Dong M, Lin K, Han J, et al. Detection of RAGE expression and its application to diabetic wound age estimation. Int J Legal Med. 2017;131:691-698 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; 1:400; fig 8
Dong M, Li M, Chen J, Fu T, Lin K, Ye G, et al. Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production. Inflammation. 2016;39:687-99 pubmed publisher
Miyamura T, Sakamoto N, Kakugawa T, Taniguchi H, Akiyama Y, Okuno D, et al. Small molecule inhibitor of HSP47 prevents pro-fibrotic mechanisms of fibroblasts in vitro. Biochem Biophys Res Commun. 2020;530:561-565 pubmed publisher
Duerr J, Leitz D, Szczygiel M, Dvornikov D, Fraumann S, Kreutz C, et al. Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice. Nat Commun. 2020;11:2012 pubmed publisher
product information
Product Type :
Antibody
Product Name :
SERPINH1 Polyclonal Antibody
Catalog # :
PA5-27832
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Species :
Human, Mouse
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
SERPINH1 is a member of the serpin superfamily of serine proteinase inhibitors, and its expression is induced by heat shock. The SERPINH1 protein localizes to the endoplasmic reticulum lumen and binds collagen; thus it is thought to be a molecular chaperone involved in the maturation of collagen molecules. Autoantibodies to SERPINH1 have been found in patients with rheumatoid arthritis.
Immunogen :
Recombinant fragment corresponding to a region within amino acids 90 and 300 of Human HSP47
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1:100, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
Aliases :
47 kDa heat shock protein; arsenic-transactivated protein 3; AsTP 3; AsTP3; BERF-1; beta enolase repressor factor 1; CBP 1; CBP 2; CBP1; CBP2; Cell proliferation-inducing gene 14 protein; collagen binding protein 1; collagen binding protein 2; collagen-binding protein; Colligen; Colligin; Colligin 1; Colligin 2; colligin-1; colligin-2; GP46; heat shock protein 47; HGNC 1547; Hsp 47; HSP47; J6; OI10; PIG 14; PIG14; PPROM; RA A47; RA-A47; rheumatoid arthritis antigen A-47; rheumatoid arthritis-related antigen RA-A47; serine (or cysteine) peptidase inhibitor, clade H, member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2; serine (or cysteine) proteinase inhibitor, clade H (heat shock protein 47), member 2, (collagen-binding protein 2); serine (or cysteine) proteinase inhibitor, clade H, member 1; serine protease inhibitor J6; serine proteinase inhibitor, clade H (heat shock protein 47), member 1; serpin family H member 1; serpin H1; serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1); serpin peptidase inhibitor, clade H, member 1; SERPINH1; SERPINH2
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA