CYP4F2 Polyclonal Antibody | Invitrogen PA5-27769 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CYP4F2 Polyclonal Antibody

catalog :

PA5-27769

quantity :

100 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, pigs

application :

western blot

citations: 1

Reference
. Functional Characterization of 29 Cytochrome P450 4F2 Variants Identified in a Population of 8380 Japanese Subjects and Assessment of Arachidonic Acid ω-Hydroxylation. Drug Metab Dispos. 2023;51:1561-1568 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CYP4F2 Polyclonal Antibody

Catalog # :

PA5-27769

Quantity :

100 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Porcine

Applications :

Western Blot: 1:500-1:3,000

Species :

Human, Porcine

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

CYP4F isoforms are involved in the oxidation of important cellular mediators, such as leukotriene B4 (LTB4) and prostaglandins. CYP4F2 catalyzes omega-hydroxylation of LTB4 to a less potent proinflammatory eicosanoid, 20-OH-LTB4 as well as arachidonic acid. CYP4F2 is expressed in liver and kidney. Its expression is repressed by peroxisomal proliferators and induced by retinoic acid. X-linked adrenoleukodystrophy (X-ALD) is a severe neurodegenerative disorder biochemically characterized by elevated levels of very long-chain fatty acids (VLCFA). CYP4F2 participates in the omega-hydroxylation of VLCFAs, which may provide an alternative mode of treatment for X-ALD patients.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 162 and 400 of Human Cytochrome P450 4F2

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:500-1:3,000

Aliases :

20-HETE synthase; 20-hydroxyeicosatetraenoic acid synthase; Arachidonic acid omega-hydroxylase; CPF2; CYP4F2; CYPIVF2; cytochrome P450 4F2; cytochrome P450 family 4 subfamily F member 2; cytochrome P450, family 4, subfamily F, polypeptide 2; cytochrome P450, subfamily IVF, polypeptide 2; cytochrome P450-LTB-omega; Docosahexaenoic acid omega-hydroxylase; docosahexaenoic acid omega-hydroxylase CYP4F3; phylloquinone omega-hydroxylase CYP4F2; leukotriene-B(4) 20-monooxygenase 1; Leukotriene-B(4) omega-hydroxylase 1; phylloquinone omega-hydroxylase CYP4F2