Blooms Syndrome Polyclonal Antibody | Invitrogen PA5-27384 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Blooms Syndrome Polyclonal Antibody

catalog :

PA5-27384

quantity :

100 µL

price :

US 470

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:100; fig 6 immunocytochemistry; human; 1:100; fig 6	Kargaran P, Yasaei H, Anjomani Virmouni S, Mangiapane G, Slijepcevic P. Analysis of alternative lengthening of telomere markers in BRCA1 defective cells. Genes Chromosomes Cancer. 2016;55:864-76 pubmed publisher
	Tan J, Wang X, Phoon L, Yang H, Lan L. Resolution of ROS-induced G-quadruplexes and R-loops at transcriptionally active sites is dependent on BLM helicase. FEBS Lett. 2020;594:1359-1367 pubmed publisher
	Cox R, Hofley C, Tatapudy P, Patel R, Dayani Y, Betcher M, et al. Functional conservation of RecQ helicase BLM between humans and Drosophila melanogaster. Sci Rep. 2019;9:17527 pubmed publisher

image

image 1 :

Immunofluorescence analysis of paraformaldehyde-fixed A431 cells using Bloom syndrome protein (PA5-27384) antibody at 1:200 dilution.

image 2 :

Immunohistochemical analysis of paraffin-embedded Cal27 xenograft using BLM (PA5-27384) antibody at 1:100 dilution.

image 3 :

Western Blot analysis of BLM using anti-BLM Polyclonal Antibody (PA5-27384), in H1299 Cell Lysate (30 ug of cell lysate) and at a dilution of 1:1000.

product information

Product Type :

Antibody

Product Name :

Blooms Syndrome Polyclonal Antibody

Catalog # :

PA5-27384

Quantity :

100 µL

Price :

US 470

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

The protein encoded by this gene belongs to the annexin family of calcium-dependent phospholipid binding proteins some of which have been implicated in membrane-related events along exocytotic and endocytotic pathways. Annexin 5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel activity and a potential role in cellular signal transduction, inflammation, growth and differentiation. Annexin 5 has also been described as placental anticoagulant protein I, vascular anticoagulant-alpha, endonexin II, lipocortin V, placental protein 4 and anchorin CII. The gene spans 29 kb containing 13 exons, and encodes a single transcript of approximately 1.6 kb and a protein product with a molecular weight of about 35 kDa.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 1235 and 1417 of Human BLM

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

Blm; Bloom syndrome homolog; Bloom syndrome protein; Bloom syndrome protein homolog; Bloom syndrome RecQ like helicase; Bloom syndrome, RecQ helicase-like; BS; DNA helicase, RecQ-like type 2; mBLM; MGC126616; MGC131618; MGC131620; RecQ helicase homolog; recQ protein-like 3; RecQ2; RECQL2; RECQL3

more info or order :

Invitrogen product webpage