Granulins Polyclonal Antibody | Invitrogen PA5-27275 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Granulins Polyclonal Antibody

catalog :

PA5-27275

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 3

Reference
Laudisi F, Cherubini F, Di Grazia A, Dinallo V, Di Fusco D, Franzè E, et al. Progranulin sustains STAT3 hyper-activation and oncogenic function in colorectal cancer cells. Mol Oncol. 2019;13:2142-2159 pubmed publisher
Li S, Chen Y, Sun D, Bai R, Gao X, Yang Y, et al. Angiogenin Prevents Progranulin A9D Mutation-Induced Neuronal-Like Cell Apoptosis Through Cleaving tRNAs into tiRNAs. Mol Neurobiol. 2018;55:1338-1351 pubmed publisher
Yeh J, Kreimer S, Walker S, Emori M, Krystal H, Richardson A, et al. Granulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer. Genes Cancer. 2015;6:153-68 pubmed

product information

Product Type :

Antibody

Product Name :

Granulins Polyclonal Antibody

Catalog # :

PA5-27275

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

PCDGF is a glycoprotein and growth factor involved in the regulation of mitosis, early embryonic development, cell division, cell migration, cell survival, and hypothalamic differentiation. PCDGF is also known as progranulin because it is the precursor for smaller proteins known as epithelins or granulins.

Immunogen :

Recombinant fragment corresponding to a region within amino acids 278 and 585 of Human Granulins

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100-1:1,000, Immunohistochemistry (Paraffin): 1:100-1:1,000

Aliases :

acrogranin; acrogranulin; CLN11; epithelin; Epithelin precursor; Epithelin/granulin precursor; Epithelin-1; Epithelin-2; GEP; Glycoprotein of 88 Kda; GP88; granulin; Granulin A; Granulin B; Granulin C; Granulin D; Granulin E; Granulin F; Granulin G; Granulin precursor; Granulin-1; Granulin-2; Granulin-3; Granulin-4; Granulin-5; Granulin-6; Granulin-7; granulin-epithelin; granulins; Grn; Paragranulin; PC cell-derived growth factor; PCDGF; PEPI; PGRN; Proepithelin; progranulin