TGR5 Polyclonal Antibody | Invitrogen PA5-27076 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TGR5 Polyclonal Antibody

catalog :

PA5-27076

quantity :

100 µL

price :

US 474

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; 1:1000; tbl 1 immunohistochemistry - paraffin section; human; 1:1000; tbl 1	Bolier R, Tolenaars D, Kremer A, Saris J, Pares A, Verheij J, et al. Enteroendocrine cells are a potential source of serum autotaxin in men. Biochim Biophys Acta. 2016;1862:696-704 pubmed publisher
	Yu H, Zhao T, Liu S, Wu Q, Johnson O, Wu Z, et al. MRGPRX4 is a bile acid receptor for human cholestatic itch. elife. 2019;8: pubmed publisher

product information

Product Type :

Antibody

Product Name :

TGR5 Polyclonal Antibody

Catalog # :

PA5-27076

Quantity :

100 µL

Price :

US 474

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human

Applications :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids. Alternative splicing results in multiple transcript variants encoding the same protein.

Immunogen :

Synthetic peptide corresponding to a region within amino acids 264 and 330 of Human TGR5

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000

Aliases :

BG37; C16DUPq36.3; DUP7q36.3; G protein-coupled bile acid receptor 1; G protein-coupled receptor; G protein-coupled receptor TGR5; Gpbar1; GPCR; GPCR HBG37; GPCR19; GPR131; G-protein coupled bile acid receptor 1; G-protein coupled bile acid receptor BG37; G-protein coupled receptor GPCR19; hBG37; Helodermin-preferring VIP receptor; hGPCR19; M-BAR; membrane bile acid receptor; membrane-type receptor for bile acids; PACAP type III receptor; PACAP-R3; PACAP-R-3; pituitary adenylate cyclase-activating polypeptide type III receptor; Tgr5; vasoactive intestinal peptide receptor 2; vasoactive intestinal polypeptide receptor 2; vasopressive intestinal peptide receptor 2; VIP and PACAP receptor 2; VIP receptor subtype 2; Vip2; VIP2R; VIPR2; VIP-R-2; VPAC2; VPAC2 receptor; VPAC2R; VPCAP2R