Cdc73 Polyclonal Antibody | Invitrogen PA5-26189 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Cdc73 Polyclonal Antibody

catalog :

PA5-26189

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 3

Reference
Chandhok S, Pereira L, Momchilova E, Marijan D, Zapf R, Lacroix E, et al. Stress-mediated aggregation of disease-associated proteins in amyloid bodies. Sci Rep. 2023;13:14471 pubmed publisher
Theodoridis P, Bokros M, Marijan D, Balukoff N, Wang D, Kirk C, et al. Local translation in nuclear condensate amyloid bodies. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Marijan D, Tse R, Elliott K, Chandhok S, Luo M, Lacroix E, et al. Stress-specific aggregation of proteins in the amyloid bodies. FEBS Lett. 2019;593:3162-3172 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Cdc73 Polyclonal Antibody

Catalog # :

PA5-26189

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:25, Western Blot: 1:2,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Cdc73 is a tumor suppressor probably involved in transcriptional and post-transcriptional control pathways. Cdc73 is part of the PAF1 complex, a five-subunit protein complex composed of Paf1, Cdc73, Leo1, Rtf1 and Ctr9. PAF1 was first purified from yeast in association with RNA polymerase II and is believed to function in transcription elongation. The yeast PAF (yPAF) complex interacts with RNA polymerase II and coordinates the setting of histone marks associated with active transcription. In addition to coordinating events during transcription (initiation, promoter clearance, and elongation), hPAF also coordinates events in RNA quality control. Cdc73 may also be involved in cell cycle progression through the regulation of cyclin D1/PRAD1 expression.

Immunogen :

KLH conjugated synthetic peptide between 132-161 amino acids from the central region of human CDC73

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:25, Western Blot: 1:2,000

Aliases :

8430414L16Rik; BC027756; C130030P16Rik; C1orf28; C81219; Cdc73; cell division cycle 73; cell division cycle 73 Paf1/RNA polymerase II complex component-like protein; cell division cycle 73, Paf1/RNA polymerase II complex component; cell division cycle 73, Paf1/RNA polymerase II complex component, homolog; cell division cycle protein 73 homolog; FIHP; HPTJT; HRPT1; HRPT2; hyperparathyroidism 2 (with jaw tumor); hyperparathyroidism 2 homolog; hyperparathyroidism 2 protein; Hyperparathyroidism 2 protein homolog; HYX; Paf1/RNA polymerase II complex component; parafibromin; Vcell division cycle 73, Paf1/RNA polymerase II complex component, homolog