This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
ESRP1 Polyclonal Antibody
catalog :
PA5-25833
quantity :
400 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
citations: 7
Reference
Xu T, Verhagen M, Teeuwssen M, Sun W, Joosten R, Sacchetti A, et al. Tropomyosin1 isoforms underlie epithelial to mesenchymal plasticity, metastatic dissemination, and resistance to chemotherapy in high-grade serous ovarian cancer. Cell Death Differ. 2024;31:360-377 pubmed publisher
Liu D, Dredge B, Bert A, Pillman K, Toubia J, Guo W, et al. ESRP1 controls biogenesis and function of a large abundant multiexon circRNA. Nucleic Acids Res. 2023;: pubmed publisher
Mukhopadhyay D, Goel H, Xiong C, Goel S, Kumar A, Li R, et al. The calcium channel TRPC6 promotes chemotherapy-induced persistence by regulating integrin α6 mRNA splicing. Cell Rep. 2023;42:113347 pubmed publisher
Batsche E, Yi J, Mauger O, Kornobis E, Hopkins B, Hanmer Lloyd C, et al. CD44 alternative splicing senses intragenic DNA methylation in tumors via direct and indirect mechanisms. Nucleic Acids Res. 2021;49:6213-6237 pubmed publisher
Wang L, Wrobel J, Xie L, Chen X. Protocol for proteogenomic dissection of intronic splicing enhancer interactome for prediction of individualized cancer prognosis. STAR Protoc. 2021;2:100338 pubmed publisher
Wang L, Wrobel J, Xie L, Li D, Zurlo G, Shen H, et al. Novel RNA-Affinity Proteogenomics Dissects Tumor Heterogeneity for Revealing Personalized Markers in Precision Prognosis of Cancer. Cell Chem Biol. 2018;25:619-633.e5 pubmed publisher
Marzese D, Liu M, Huynh J, Hirose H, Donovan N, Huynh K, et al. Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome. Pigment Cell Melanoma Res. 2015;28:82-93 pubmed publisher
product information
Product Type :
Antibody
Product Name :
ESRP1 Polyclonal Antibody
Catalog # :
PA5-25833
Quantity :
400 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Ammonium sulfate precipitation
Host :
Rabbit
Reactivity :
Human
Applications :
Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:2,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.
Immunogen :
KLH conjugated synthetic peptide between 182-211 amino acids of human ESRP1
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:2,000
Aliases :
2210008M09Rik; A630065D16; BC031468; epithelial splicing regulatory protein 1; Esrp1; Rbm35a; RGD1560481; RMB35A; RNA binding motif protein 35A; RNA-binding motif protein 35A; RNA-binding protein 35A
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA