HVCN1 Polyclonal Antibody | Invitrogen PA5-24964 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HVCN1 Polyclonal Antibody

catalog :

PA5-24964

quantity :

400 uL

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, flow cytometry

citations: 2

Reference
Perelman S, James D, Boguslawski K, Nelson C, Ilmain J, Zwack E, et al. Genetic variation of staphylococcal LukAB toxin determines receptor tropism. Nat Microbiol. 2021;6:731-745 pubmed publisher
Ventura C, León I, Asuaje A, Martin P, Enrique N, Nuñez M, et al. Differential expression of the long and truncated Hv1 isoforms in breast-cancer cells. J Cell Physiol. 2020;235:8757-8767 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HVCN1 Polyclonal Antibody

Catalog # :

PA5-24964

Quantity :

400 uL

Price :

US 464.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:10-1:50, Western Blot: 1:1,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

HVCN1 (hydrogen voltage-gated channel 1), a voltage gated proton channel protein that is highly expressed in immune tissues, mediates the proton conductances required by phagocytic leukocytes for the oxidative burst that underlies microbial killing. HVCN1 moderates the voltage-dependent proton permeability of excitable membranes by allowing the flow of protons in accordance to their electrochemical gradient. HVCN1 is sensitive to zinc ions, and can be inhibited by them. HVCN1 may represent a new therapeutic target for B cell malignancies on continued signaling via the B cell antigen receptor.

Immunogen :

KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HVCN1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:10-1:50, Western Blot: 1:1,000

Aliases :

0610039P13Rik; AI450555; BTS; HV1; Hvcn1; hydrogen voltage gated channel 1; hydrogen voltage-gated channel 1; mVSOP; RGD1310788; UNQ578/PRO1140; Voltage sensor domain-only protein; voltage-gated hydrogen channel 1; Vsop; Vsop.