Folate Receptor alpha Polyclonal Antibody | Invitrogen PA5-24186 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

Folate Receptor alpha Polyclonal Antibody

catalog :

PA5-24186

quantity :

400 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

citations: 3

Reference
Shivange G, Mondal T, Lyerly E, Bhatnagar S, Landen C, Reddy S, et al. A patch of positively charged residues regulates the efficacy of clinical DR5 antibodies in solid tumors. Cell Rep. 2021;37:109953 pubmed publisher
Mondal T, Shivange G, Tihagam R, Lyerly E, Battista M, Talwar D, et al. Unexpected PD-L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies. EMBO Mol Med. 2021;13:e12716 pubmed publisher
Kleinmanns K, Fosse V, Davidson B, de Jalón E, Tenstad O, Bjørge L, et al. CD24-targeted intraoperative fluorescence image-guided surgery leads to improved cytoreduction of ovarian cancer in a preclinical orthotopic surgical model. EBioMedicine. 2020;56:102783 pubmed publisher

product information

Product Type :

Antibody

Product Name :

Folate Receptor alpha Polyclonal Antibody

Catalog # :

PA5-24186

Quantity :

400 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human

Applications :

Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:2,000

Species :

Human

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

The protein encoded by this gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transport 5-methyltetrahydrofolate into cells. This gene product is a secreted protein that either anchors to membranes via a glycosyl-phosphatidylinositol linkage or exists in a soluble form. Mutations in this gene have been associated with neurodegeneration due to cerebral folate transport deficiency. Due to the presence of two promoters, multiple transcription start sites, and alternative splicing, multiple transcript variants encoding the same protein have been found for this gene.

Immunogen :

KLH conjugated synthetic peptide between 33-68 amino acids from the N-terminal region of human FOLR1

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 1:25, Immunohistochemistry (Paraffin): 1:1,000, Western Blot: 1:2,000

Aliases :

66/67kDa; AA407891; adult folate-binding protein; eIF3 p66; EIF3D; eIF3d {ECO:0000255; eIF3p66; eIF3-p66; EIF3S7; eIF-3-zeta; eIF3-zeta; eIF-3-zeta {ECO:0000255; Eukaryotic translation initiation factor 3 subunit 7; eukaryotic translation initiation factor 3 subunit 7 {ECO:0000255; eukaryotic translation initiation factor 3 subunit D; eukaryotic translation initiation factor 3 subunit D {ECO:0000255; eukaryotic translation initiation factor 3, subunit 7 (zeta); eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa; eukaryotic translation initiation factor 3, subunit D; FBP; Fbp1; folate binding protein; folate binding protein 1; folate receptor 1; folate receptor 1 (adult); folate receptor alpha; Folate receptor, adult; folate-binding protein 1; Folbp1; Folbp-1; FOLR; FOLR1; FR-alpha; HAMAP-Rule:MF_03003}; KB cells FBP; MOv18; Ovarian tumor-associated antigen MOv18; translation initiation factor eIF3 p66; translation initiation factor eIF3 p66 subunit