CAMK2N1 Polyclonal Antibody | Invitrogen PA5-23740 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CAMK2N1 Polyclonal Antibody

catalog :

PA5-23740

quantity :

400 uL

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot

citations: 2

Reference
Wu C, Miao C, Tang Q, Zhou X, Xi P, Chang P, et al. MiR-129-5p promotes docetaxel resistance in prostate cancer by down-regulating CAMK2N1 expression. J Cell Mol Med. 2020;24:2098-2108 pubmed publisher
Eizuka K, Nakashima D, Oka N, Wagai S, Takahara T, Saito T, et al. SYT12 plays a critical role in oral cancer and may be a novel therapeutic target. J Cancer. 2019;10:4913-4920 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CAMK2N1 Polyclonal Antibody

Catalog # :

PA5-23740

Quantity :

400 uL

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography, Protein A

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Western Blot: 1:1,000

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity). Plays a role in the maintenance of long-term retrieval- induced memory in response to contextual fear (By similarity). Modulates blood pressure and vascular reactivity via regulation of CAMK2 activity in addition to regulation of left ventricular mass (By similarity). Mediates the NLRP3 inflammasome in cardiomyocytes via acting as an inhibitor of the MAPK14/p38 and MAPK8/JNK pathways, thereby regulating ventricular remodeling and cardiac rhythm post- myocardial infarction (By similarity). Negatively effects insulin sensitivity and promotes lipid formation in adipose tissues independent of CAMK2 signaling (By similarity).

Immunogen :

KLH conjugated synthetic peptide between 37-65 amino acids from the C-terminal region of human CAMK2N1

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:1,000

Aliases :

1810006K23Rik; AI848599; AI891706; calcium/calmodulin dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor 1; calcium/calmodulin-dependent protein kinase II inhibitor alpha; Camk2n1; CaMKII inhibitor protein alpha; caMKII inhibitory protein alpha; CaMKIINalpha; CaMKIIN-alpha; mCaMKIINalpha; PRO1489; RP11-401M16.1