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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
MRP3 Polyclonal Antibody
catalog :
PA5-23653
quantity :
400 uL
price :
US 474.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; fig 3, 4
Liu X, Yao D, Liu C, Cao Y, Yang Q, Sun Z, et al. Overexpression of ABCC3 promotes cell proliferation, drug resistance, and aerobic glycolysis and is associated with poor prognosis in urinary bladder cancer patients. Tumour Biol. 2016;37:8367-74 pubmed publisher
Šeborová K, Kloudova Spalenkova A, Koucká K, Holý P, Ehrlichova M, Wang C, et al. The Role of TRIP6, ABCC3 and CPS1 Expression in Resistance of Ovarian Cancer to Taxanes. Int J Mol Sci. 2021;23: pubmed publisher
product information
Product Type :
Antibody
Product Name :
MRP3 Polyclonal Antibody
Catalog # :
PA5-23653
Quantity :
400 uL
Price :
US 474.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography, Protein A
Host :
Rabbit
Reactivity :
Human
Applications :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000
Species :
Human
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Immunogen :
KLH conjugated synthetic peptide between 899-925 amino acids from the central region of human ABCC3
Format :
Liquid
Applications w/Dilutions :
Flow Cytometry: 1:10-1:50, Immunohistochemistry (Paraffin): 1:10-1:50, Western Blot: 1:1,000
Aliases :
ABC31; ABCC3; ATP binding cassette subfamily C member 3; ATP-binding cassette sub-family C member 3; ATP-binding cassette, subfamily C (CFTR/MRP), member 3; ATP-binding cassette, sub-family C (CFTR/MRP), member 3; canalicular multispecific organic anion transporter 2; canicular multispecific organic anion transporter; cMOAT2; DKFZp686E22157; EST90757; MLP2; MLP-2; MOAT-D; Mrp3; MRP-like protein 2; multidrug resistance associated protein; multidrug resistance protein 3; multidrug resistance-associated protein 3; multi-specific organic anion transporter D; organic anion transporter
more info or order :
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA