This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
NUMB Polyclonal Antibody
catalog :
PA5-23486
quantity :
100 ug
price :
US 514.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, bovine
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
NUMB Polyclonal Antibody
Catalog # :
PA5-23486
Quantity :
100 ug
Price :
US 514.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Bovine, Human, Mouse, Non-human primate, Rat
Applications :
Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 1-2 ug/mL
Species :
Bovine, Human, Mouse, Non-human primate, Rat
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Protein NUMB homolog is an evolutionarily conserved protein that controls the differentiation of neuronal progenitor cells. Recent studies have revealed that NUMB functions in clathrin-dependent endocytosis by binding to the AP-2 complex. NUMB is also expressed in postmitotic neurons and plays a role in axonal growth. Neural cells expressing Numb isoforms with short phosphotyrosine-binding (SPTB) domain undergo extensive neurite outgrowth, an effect that can be blocked by voltage-gated Ca2+ channel (VGCC) inhibitor or by Ca2+ chelator.
Immunogen :
A synthetic peptide corresponding to amino acids 12-40  of human NUMB
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 5 ug/mL, Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 1-2 ug/mL
Aliases :
c14_5527; C14orf41; h-Numb; mnb; m-Nb; m-numb; Nb; NUMB; NUMB endocytic adaptor protein; numb gene homolog; numb gene homolog (Drosophila); numb homolog; numb homolog (Drosophila); NUMB isoform 3; Numb variant 1; Numb variant 2; NUMB, endocytic adaptor protein; protein numb homolog; Protein S171; PTB domain protein; S171
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA