This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
DACH1 Polyclonal Antibody
catalog :
PA5-23483
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs, chicken, bovine, domestic horse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
DACH1 Polyclonal Antibody
Catalog # :
PA5-23483
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate
Applications :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 5-7 ug/mL
Species :
Bovine, Canine, Chicken, Equine, Human, Mouse, Non-human primate
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
Transcription factor that is involved in regulation of organogenesis. Seems to be a regulator of SIX1, SIX6 and probably SIX5. Corepression of precursor cell proliferation in myoblasts by SIX1 is switched to coactivation through recruitment of EYA3 to the SIX1-DACH1 complex. Transcriptional activation seems also to involve association of CREBBP. Seems to act as a corepressor of SIX6 in regulating proliferation by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter. Inhibits TGF-beta signaling through interaction with SMAD4 and NCOR1. Binds to chromatin DNA via its DACHbox-N domain.
Immunogen :
Amino acids 474-501 of human Dach1
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 5-7 ug/mL
Aliases :
Dac; dac homolog; DACH; Dach1; dachshund 1; dachshund 1 (Drosophila); dachshund family transcription factor 1; dachshund homolog 1; FLJ10138; OTTHUMP00000040839; RP11-512J14.1
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA