TRIF Polyclonal Antibody | Invitrogen PA5-23467 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TRIF Polyclonal Antibody

catalog :

PA5-23467

quantity :

100 ug

price :

US 454.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, pigs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; mouse; loading ...; fig 4e western blot; human; loading ...; fig 7h	Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TRIF Polyclonal Antibody

Catalog # :

PA5-23467

Quantity :

100 ug

Price :

US 454.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Mouse, Porcine, Rat

Applications :

Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-Dependent, Western Blot: 1-2 ug/mL

Species :

Mouse, Porcine, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

Involved in innate immunity against invading pathogens. Adapter used by TLR3 and TLR4 (through TICAM2) to mediate NF-kappa-B and interferon-regulatory factor (IRF) activation, and to induce apoptosis. Ligand binding to these receptors results in TRIF recruitment through its TIR domain. Distinct protein-interaction motifs allow recruitment of the effector proteins TBK1, TRAF6 and RIPK1, which in turn, lead to the activation of transcription factors IRF3 and IRF7, NF-kappa-B and FADD respectively.

Immunogen :

Synthetic peptide made to an internal portion of the mouse TRIF protein (between amino acids 100-180) [UniProt Q80UF7].

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:10-1:100, Immunohistochemistry (Paraffin): 1:200, Immunoprecipitation: Assay-Dependent, Western Blot: 1-2 ug/mL

Aliases :

AW046014; AW547018; hCG_39321; HSD34; IIAE6; MyD88-3; Proline-rich, vinculin and TIR domain-containing protein B; PRVTIRB; Putative NF-kappa-B-activating protein 502H; RNF36; TI; Ticam1; TICAM-1; TIR domain containing adaptor inducing interferon-beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; TIR domain-containing adaptor inducing interferon-beta; TIR-domain containing adaptor inducing interferon-beta; toll like receptor adaptor molecule 1; toll-interleukin 1 receptor domain-containing adapter protein inducing interferon-beta; toll-interleukin I receptor domain containing adaptor molecule 1; toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; toll-like receptor adaptor molecule 1; TRIF

more info or order :

Invitrogen product webpage