SOX9 Polyclonal Antibody | Invitrogen PA5-23383 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

SOX9 Polyclonal Antibody

catalog :

PA5-23383

quantity :

100 ug

price :

US 474.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

domestic goat, human, mouse, rat, dogs, cat, domestic sheep

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Reference
Grissom S, Semevolos S, Duesterdieck Zellmer K. Role of cartilage and bone matrix regulation in early equine osteochondrosis. Bone Rep. 2023;18:101653 pubmed publisher
Xu Y, Zhang T, Chen Y, Shi Q, Li M, Qin T, et al. Isolation and Characterization of Multipotent Canine Urine-Derived Stem Cells. Stem Cells Int. 2020;2020:8894449 pubmed publisher
Xiao D, Bi R, Liu X, Mei J, Jiang N, Zhu S. Notch Signaling Regulates MMP-13 Expression via Runx2 in Chondrocytes. Sci Rep. 2019;9:15596 pubmed publisher

product information

Product Type :

Antibody

Product Name :

SOX9 Polyclonal Antibody

Catalog # :

PA5-23383

Quantity :

100 ug

Price :

US 474.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Canine, Feline, Goat, Human, Mouse, Non-human primate, Ovine, Rat

Applications :

Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2-5 ug/mL

Species :

Canine, Feline, Goat, Human, Mouse, Non-human primate, Ovine, Rat

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

SOX9 has a role in sex determination and differentiation of Sertoli cells. It is involved in chondrogenesis and regulates the expression of other genes involved in chondrogenesis by acting as a transcription factor for these genes. Translocation of this gene can cause campomelic dysplasia. SOX9 is involved in the formation of testes from the indifferent fetal gonads. It is a major molecular component of the neuron-glia switch in developing spinal cord. During normal development, SOX9 allows the prostate epithelium to outgrow into the mesenchyme and then provides basal cell support for development and maintenance of the luminal epithelium. These functions of SOX9 are subverted in prostate cancer to support tumor growth and invasion. SOX9 may direct the formation of neural crest precursors and the development of a range of neural crest derivative. It has a transcriptional regulation in melanin production in cells. Northern blot analysis shows its expression on adult testis, adult heart, and fetal brain.

Immunogen :

A portion of amino acids 225-275 of human SOX9 was used as the immunogen for this antibody.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2-5 ug/mL

Aliases :

2010306G03Rik; AV220920; CMD1; CMPD1; mKIAA4243; SOX 9; Sox9; SOX-9; Sox9 transcription factor; SRA1; SRXX2; SRXY10; SRY (sex determining region Y)-box 9; SRY (sex determining region Y)-box 9 (campomelic dysplasia, autosomal sex-reversal); SRY (sex determining region Y)-box9; SRY (sex-determining region Y)-box 9 protein; SRY box 9; SRY-box 9; SRY-Box 9 ; SRY-box containing 9; SRY-box containing gene 9; SRY-box containing protein 9; SRY-box transcription factor 9; SRY-related HMG-box, gene 9; transcription activator Sox9; transcription factor SOX-9