HES1 Polyclonal Antibody | Invitrogen PA5-23283 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

HES1 Polyclonal Antibody

catalog :

PA5-23283

quantity :

100µL

price :

US 390

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Li H, Sun S, Lei Q, Lei P, Cai X, Wan C, et al. M1-Polarized Macrophages Promote Self-Renewing Phenotype of Hepatic Progenitor Cells with Jagged1-Notch Signalling Involved: Relevance in Primary Sclerosing Cholangitis. J Immunol Res. 2018;2018:4807145 pubmed publisher

product information

Product Type :

Antibody

Product Name :

HES1 Polyclonal Antibody

Catalog # :

PA5-23283

Quantity :

100µL

Price :

US 390

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bovine, Human, Mouse, Non-human primate, Rat

Applications :

Immunohistochemistry (Paraffin): 1:1000-1:2000

Species :

Bovine, Human, Mouse, Non-human primate, Rat

Isotype :

IgG

Storage :

-20° C, Avoid Freeze/Thaw Cycles

Description :

HES1 is a nuclear protein belonging to th basic helix-loop-helix family of transcription factors with a basic helix-loop-helix (bHLH) domain and an Orange domain. The basic domain of HES1 contains a helix interrupting protein that binds to the N-box rather than the canonical E-box. An immediate early response gene to growth factor, HES1 is reported as having a dual function of both transcriptional activator and silencer of acid alpha-glucosidase (GAA), thus contributing to the subtle tissue-specific control of housekeeping genes such as GAA. HES1 a transcriptional repressor of genes which require a bHLH protein for their transcription and also the formation of a complex with a corepressor protein (Groucho) such as TLE2. HES1 may act as a negative regulator of myogenesis by inhibiting the functions of MYOD1 and ASH1.

Immunogen :

Synthetic peptide (249 TSNSGTSVGPNAVSPSSG 266) of HES1 protein.

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 1:1000-1:2000

Aliases :

HES-1, HHL, HRY, bHLHb39, class B basic helix-loop-helix protein 39, hairy homolog, hairy-like protein, transcription factor HES-1