This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
CUEDC2 Polyclonal Antibody
catalog :
PA5-23265
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, dogs, bovine, pigs , domestic horse
application :
western blot
product information
Product Type :
Antibody
Product Name :
CUEDC2 Polyclonal Antibody
Catalog # :
PA5-23265
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
protein A
Host :
Rabbit
Reactivity :
Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine
Applications :
Western Blot: 0.5-1 ug/mL
Species :
Bovine, Canine, Equine, Human, Mouse, Non-human primate, Porcine
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
The CUE (coupling of ubiquitin conjugation to endoplasmic reticulum degradation) domain is an evolutionarily conserved, approximately 40 amino acid monoubiquitin-binding domain that mediates intramolecular monoubiquitylation. CUE domains are present in eukaryotic proteins that are involved in ubiquitination and protein trafficking pathways and may be required for ubiquitination of the proteins in which they are found. CUEDC2 (CUE domain-containing protein 2) was found through a yeast two-hybrid screening as a protein that interacts with the progesterone receptor (PR) and promotes progesterone-induced PR degradation by the ubiquitin-proteasome pathway. CUEDC2 also decreases the sumoylation of PR. CUEDC2 has also been found to interact with IKK-alpha and IKK-beta and decrease the activation of NF-kappa-B by decreasing the activation of IKK.
Immunogen :
A portion of amino acid 250-287 of human CUEDC2
Format :
Liquid
Applications w/Dilutions :
Western Blot: 0.5-1 ug/mL
Aliases :
3010002G01Rik; bA18I14.5; C10orf66; CUE domain containing 2; CUE domain-containing protein 2; CUEDC2; HOYS6; Unknown (protein for MGC:128745)
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA