This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TRBP Polyclonal Antibody
catalog :
PA5-23175
quantity :
100 ug
price :
US 464.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, domestic horse
application :
western blot, immunohistochemistry, immunohistochemistry - paraffin section
product information
Product Type :
Antibody
Product Name :
TRBP Polyclonal Antibody
Catalog # :
PA5-23175
Quantity :
100 ug
Price :
US 464.00
Clonality :
Polyclonal
Purity :
Protein G
Host :
Rabbit
Reactivity :
Equine, Human, Non-human primate
Applications :
Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 5-8 ug/mL
Species :
Equine, Human, Non-human primate
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.
Immunogen :
A portion of amino acids 340-366 of human TRBP
Format :
Liquid
Applications w/Dilutions :
Immunohistochemistry (Paraffin): 5-10 ug/mL, Western Blot: 5-8 ug/mL
Aliases :
fj51e12; HAMAP-Rule:MF_03034}; LOQS; Prbp; PRM-1 RNA-binding protein; protamine-1 RNA-binding protein; RISC-loading complex subunit tarbp2; RISC-loading complex subunit TARBP2 {ECO:0000255; TAR (HIV) RNA binding protein 2; TAR (HIV) RNA-binding protein 2; TAR (HIV) RNA-binding protein TRBP1; TAR (HIV-1) RNA binding protein 2; TAR RNA binding protein 2; TAR RNA-binding protein 2; TARBP2; TARBP2 subunit of RISC loading complex; TARBP2, RISC loading complex RNA binding subunit; trans-activation responsive RNA-binding protein; trans-activation-responsive RNA-binding protein; TRBP; TRBP1; TRBP2; wu:fj51e12; zgc:63778
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA