DAZL Polyclonal Antibody | Invitrogen PA5-23152 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

DAZL Polyclonal Antibody

catalog :

PA5-23152

quantity :

100 µL

price :

375 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, dogs, bovine

application :

western blot

product information

Product Type :

Antibody

Product Name :

DAZL Polyclonal Antibody

Catalog # :

PA5-23152

Quantity :

100 µL

Price :

375 USD

Clonality :

Polyclonal

Host :

Rabbit

Reactivity :

Bovine, Canine, Human, Mouse, Non-human primate

Applications :

Western Blot: 1:5000

Species :

Bovine, Canine, Human, Mouse, Non-human primate

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Protein expression pattern show that DAZL is involved in mitosis and meiosis of human germ cell. The DAZL gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females.The protein is expressed in germ cells of diverse mammalian species. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In humans, DAZL is expressed in primordial germ cells, adult testis, and the ovary. It plays a central role during spermatogenesis. Defects in DAZL may cause infertility due to severe oligozoospermia (az) and non obstructive azoospermia. The concentrations of DAZL transcripts were lower in men with spermatogenic failure. Drosophila and mouse mutants that have lost DAZ homologous gene function found to be azoospermic, just as with human azoospermia DAZ. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome.

Immunogen :

Synthetic peptide (50 RMDETEIRSFFARYG 64) of DAZL protein.

Format :

Liquid

Applications w/Dilutions :

Western Blot: 1:5000

Aliases :

DAZ homolog; DAZH; DAZL; Dazl1; Dazla; Daz-like; DAZ-like autosomal; deleted in azoospermia like; deleted in azoospermia protein 3; deleted in azoospermia-like; Deleted in azoospermia-like 1; deleted in azoospermia-like protein; germline specific RNA binding protein; HGNC:2685; MGC26406; spermatogenesis gene on the Y-like autosomal; SPGYLA; SPGY-like-autosomal; testis secretory sperm-binding protein Li 204a; Tpx2; Tpx-2