ROR gamma Polyclonal Antibody | Invitrogen PA5-23148 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

ROR gamma Polyclonal Antibody

catalog :

PA5-23148

quantity :

100 ug

price :

US 514.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 6

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; loading ...	Kong W, Tsuyama N, Inoue H, Guo Y, Mokuda S, Nobukiyo A, et al. Long-chain saturated fatty acids in breast milk are associated with the pathogenesis of atopic dermatitis via induction of inflammatory ILC3s. Sci Rep. 2021;11:13109 pubmed publisher
immunohistochemistry; human; 1:4000; loading ...; fig 4b immunocytochemistry; mouse; 1:500; fig s4d immunohistochemistry; mouse; 1:4000; loading ...; fig 4i western blot; mouse; loading ...; fig s4h	Lytle N, Ferguson L, Rajbhandari N, Gilroy K, Fox R, Deshpande A, et al. A Multiscale Map of the Stem Cell State in Pancreatic Adenocarcinoma. Cell. 2019;177:572-586.e22 pubmed publisher
	Ahmed L, Mohamed A, Abd El Haleim E, El Tanbouly D. Boosting Akt Pathway by Rupatadine Modulates Th17/Tregs Balance for Attenuation of Isoproterenol-Induced Heart Failure in Rats. Front Pharmacol. 2021;12:651150 pubmed publisher
	Chen J, Chen Y, Shi Y, Ding S, Shen L, Wang R, et al. VX-765 reduces neuroinflammation after spinal cord injury in mice. Neural Regen Res. 2021;16:1836-1847 pubmed publisher
	Lenkiewicz E, Malasi S, Hogenson T, Flores L, Barham W, Phillips W, et al. Genomic and Epigenomic Landscaping Defines New Therapeutic Targets for Adenosquamous Carcinoma of the Pancreas. Cancer Res. 2020;80:4324-4334 pubmed publisher
	Chen Y, Wang S, Shi Y, Chen J, Ding S, Tang J, et al. CRID3, a blocker of apoptosis associated speck like protein containing a card, ameliorates murine spinal cord injury by improving local immune microenvironment. J Neuroinflammation. 2020;17:255 pubmed publisher

product information

Product Type :

Antibody

Product Name :

ROR gamma Polyclonal Antibody

Catalog # :

PA5-23148

Quantity :

100 ug

Price :

US 514.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Human, Mouse

Applications :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 0.5-2 ug/mL

Species :

Human, Mouse

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

ROR gamma is a 560 amino acid novel DNA-binding transcription factor belonging to the ROR/RZR orphan nuclear receptor subfamily. Reports suggest thatROR gammais a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR gamma shares 50 to 51% sequence identity with RORA and RORB and is 88% identical to mouse ROR gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues.

Immunogen :

A portion of amino acids 1-50 of human ROR gamma/RORC/NR1F3

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: Assay-Dependent, Immunohistochemistry (Paraffin): 10 ug/mL, Immunoprecipitation: Assay-Dependent, Western Blot: 0.5-2 ug/mL

Aliases :

IMD42; Nr1f3; Nuclear receptor ROR-gamma; nuclear receptor RZR-gamma; Nuclear receptor subfamily 1 group F member 3; RAR related orphan receptor C; RAR-related orphan nuclear receptor variant 2; RAR-related orphan receptor C; RAR-related orphan receptor C, isoform a; RAR-related orphan receptor gamma; retinoic acid-binding receptor gamma; retinoid-related orphan receptor gamma; retinoid-related orphan receptor-gamma; RORC; RORG; RORgamma; RZRG; RZR-GAMMA; Thor; Thymus orphan receptor; TOR

more info or order :

Invitrogen product webpage