TICAM2 Polyclonal Antibody | Invitrogen PA5-23115 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

TICAM2 Polyclonal Antibody

catalog :

PA5-23115

quantity :

100 ug

price :

US 464.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Reference
Bugueno I, Benkirane Jessel N, Huck O. Implication of Toll/IL-1 receptor domain containing adapters in Porphyromonas gingivalis-induced inflammation. Innate Immun. 2021;27:324-342 pubmed publisher

product information

Product Type :

Antibody

Product Name :

TICAM2 Polyclonal Antibody

Catalog # :

PA5-23115

Quantity :

100 ug

Price :

US 464.00

Clonality :

Polyclonal

Purity :

protein A

Host :

Rabbit

Reactivity :

Human, Non-human primate

Applications :

Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 0.5-2 ug/mL

Species :

Human, Non-human primate

Isotype :

IgG

Storage :

Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.

Description :

TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.

Immunogen :

Within the range of amino acids 87-124 of human TRAM (TICAM2) protein

Format :

Liquid

Applications w/Dilutions :

Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 0.5-2 ug/mL

Aliases :

B430113A10; cytoplasmic adaptor; MyD88-4; NF-kappa-B-activating protein 502; putative NF-kappa-B-activating protein 502; TAG; TICAM2; TICAM-2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter protein; TIRAP3; Tirp; toll like receptor adaptor molecule 2; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; toll/interleukin-1 receptor domain-containing protein; Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2; toll-like receptor adaptor molecule 2; toll-like receptor adaptor protein 3; Tram; Trif; TRIF-related adapter molecule; TRIF-related adapter molecule TRAM; TRIF-related adaptor molecule