CX3CL1 Polyclonal Antibody | Invitrogen PA5-23062 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CX3CL1 Polyclonal Antibody

catalog :

PA5-23062

quantity :

100 µL

price :

US 460.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 3

Reference
Aguiar T, Rivas M, Costa S, Maschietto M, Rodrigues T, Sobral de Barros J, et al. Insights Into the Somatic Mutation Burden of Hepatoblastomas From Brazilian Patients. Front Oncol. 2020;10:556 pubmed publisher
Lannes N, Garcia Nicolàs O, Démoulins T, Summerfield A, Filgueira L. CX3CR1-CX3CL1-dependent cell-to-cell Japanese encephalitis virus transmission by human microglial cells. Sci Rep. 2019;9:4833 pubmed publisher
Hoffmann Vold A, Weigt S, Palchevskiy V, Volkmann E, Saggar R, Li N, et al. Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis. PLoS ONE. 2018;13:e0206545 pubmed publisher

product information

Product Type :

Antibody

Product Name :

CX3CL1 Polyclonal Antibody

Catalog # :

PA5-23062

Quantity :

100 µL

Price :

US 460.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Gerbil, Human, Mouse

Applications :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:250, Western Blot: Assay-Dependent

Species :

Gerbil, Human, Mouse

Isotype :

IgG

Storage :

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Description :

Chemokines are a family of proteins associated with the trafficking of leukocytes in immune surveillance and inflammatory cell recruitment. They are classified based on the positions of key cysteine residues. CX3CL1 is a CX3C chemokine known to induce adhesion and migration of leukocytes mediated by a membrane-bound and soluble form respectively. Recent experiments have shown that CX3CL1 can suppress the production of nitrous oxide, interleukin-6, and TNF-a in activated microglia and neuronal cells, suggesting that it may act as an intrinsic inhibitor against neurotoxicity by activated microglia. Its receptor, CX3CR1, also functions as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by CX3CL1.

Immunogen :

A synthetic peptide made to an internal region of the human CX3CL protein (within residues 20-150).

Format :

Liquid

Applications w/Dilutions :

Immunocytochemistry: 1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): 1:250, Western Blot: Assay-Dependent

Aliases :

A-152E5.2; AB030188; ABCD-3; Acc1; AI848747; C3Xkine; chemokine (C-X3-C motif) ligand 1; CX3C; CX3C membrane-anchored chemokine; C-X3-C motif chemokine 1; C-X3-C motif chemokine ligand 1; Cx3cl1; CXC3; CXC3C; D8Bwg0439e; Fkn; Fractalkine; neurotactin; NTN; NTT; Processed fractalkine; SCYD1; small inducible cytokine subfamily D (Cys-X3-Cys), member 1 (fractalkine, neurotactin); small inducible cytokine subfamily D (Cys-X3-Cys), member-1; small inducible cytokine subfamily D, 1; small-inducible cytokine D1