CCR2 Polyclonal Antibody | Invitrogen PA5-23037 product information

product summary

company name :

Invitrogen

other brands :

NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

product type :

antibody

product name :

CCR2 Polyclonal Antibody

catalog :

PA5-23037

quantity :

100 uL

price :

US 470.00

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse, rat, bovine, cat

application :

western blot, immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

Invitrogen product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; mouse; 1:50; loading ...; fig s3c	Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed publisher
	Meneghetti M, Kaur J, Sui K, S xf8 rensen J, Berg R, Markos C. Soft monolithic infrared neural interface for simultaneous neurostimulation and electrophysiology. Light Sci Appl. 2023;12:127 pubmed publisher
	Do C, Ford B, Lee D, Tan C, Escobar P, Wagner B. Gadolinium-based contrast agents: Stimulators of myeloid-induced renal fibrosis and major metabolic disruptors. Toxicol Appl Pharmacol. 2019;375:32-45 pubmed publisher
	Do C, Drel V, Tan C, Lee D, Wagner B. 'Nephrogenic' systemic fibrosis is mediated by myeloid C-C chemokine receptor 2. J Invest Dermatol. 2019;: pubmed publisher

product information

Product Type :

Antibody

Product Name :

CCR2 Polyclonal Antibody

Catalog # :

PA5-23037

Quantity :

100 uL

Price :

US 470.00

Clonality :

Polyclonal

Purity :

Antigen affinity chromatography

Host :

Rabbit

Reactivity :

Bovine, Feline, Human, Rat

Applications :

Flow Cytometry: 5 ug/mL, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2 ug/mL

Species :

Bovine, Feline, Human, Rat

Isotype :

IgG

Storage :

-20 C, Avoid Freeze/Thaw Cycles

Description :

CCR2, a chemokine receptor, is a regulator of monocyte/macrophage traffickings and is upregulated in response to inflammation. Resistance to HIV-1 infection or delayed progression to AIDS may be linked to CCR2 polymorphisms. The ligand for CCR2 is monocyte chemoattractant protein (MCP-1), a chemokine produced by endothelial cells, smooth muscle cells, and macrophages. Activation of monocytes by MCP-1 may mediate the monocytic infiltration of tissues in atherosclerosis and other inflammatory disorders including rheumatoid arthritis, alveolitis, and tumor infiltration. Two isoforms are produced by alternative splicing. CCR2 has been reported to be expressed in a wide variety of tissues, including blood, brain, heart, kidney, liver, lung, ovary, pancreas, spinal cord, spleen, thymus, and vessel. Increased expression of CCR2 has been documented in CD3+ lymphocytes in rheumatoid arthritis. ESTs have been isolated from liver/spleen and prostate libraries.

Immunogen :

Synthetic peptide made to an N-terminal portion of the human CCR2 protein (within residues 20-100).

Format :

Liquid

Applications w/Dilutions :

Flow Cytometry: 5 ug/mL, Immunocytochemistry: 1:50, Immunohistochemistry (Paraffin): 5 ug/mL, Western Blot: 2 ug/mL

Aliases :

C-C chemokine receptor type 2; C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR); C-C CKR-2; C-C motif chemokine receptor 2; Cc-ckr2; CC-CKR-2; Ccr2; CCR-2; Ccr2a; CCR2B; CD192; CD192 antigen; chemoattractant protein-1 receptor; chemokine (C-C motif) receptor 2; chemokine (C-C) receptor 2; chemokine receptor CCR2; Ckr2; Ckr2a; Ckr2b; CMKBR2; hCG_14621; JE/FIC receptor; Mcp1 receptor; MCP-1 receptor; Mcp1r; MCP-1-R; MIP-1 alphaR; mJe-r; Monocyte chemoattractant protein 1 receptor; monocyte chemotactic protein 1 receptor

more info or order :

Invitrogen product webpage