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company name :
Invitrogen
other brands :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
product type :
antibody
product name :
TMEM97 Polyclonal Antibody
catalog :
PA5-23003
quantity :
100 uL
price :
US 470.00
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
Invitrogen product webpage
citations: 3
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig s1-5a
Miller Vedam L, Bräuning B, Popova K, Schirle Oakdale N, Bonnar J, Prabu J, et al. Structural and mechanistic basis of the EMC-dependent biogenesis of distinct transmembrane clients. elife. 2020;9: pubmed publisher
Wang H, Peng Z, Li Y, Sahn J, Hodges T, Chou T, et al. σ2R/TMEM97 in retinal ganglion cell degeneration. Sci Rep. 2022;12:20753 pubmed publisher
Cortesi M, Zamagni A, Pignatta S, Zanoni M, Arienti C, Rossi D, et al. Pan-Sigma Receptor Modulator RC-106 Induces Terminal Unfolded Protein Response In In Vitro Pancreatic Cancer Model. Int J Mol Sci. 2020;21: pubmed publisher
product information
Product Type :
Antibody
Product Name :
TMEM97 Polyclonal Antibody
Catalog # :
PA5-23003
Quantity :
100 uL
Price :
US 470.00
Clonality :
Polyclonal
Purity :
Antigen affinity chromatography
Host :
Rabbit
Reactivity :
Human, Mouse
Applications :
Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Paraffin): 1:200, Western Blot: 2 ug/mL
Species :
Human, Mouse
Isotype :
IgG
Storage :
Store at 4 C short term. For long term storage, store at -20 C, avoiding freeze/thaw cycles.
Description :
TMEM97, or MAC30, is a conserved transmembrane protein that helps regulate cellular cholesterol levels through colocalization with NPC1. TMEM97 has also been linked to several cancers including breast, pancreatic, colorectal and ovarian cancers.
Immunogen :
Synthetic peptide made to an internal portion of the human protein (within residues 105-155.
Format :
Liquid
Applications w/Dilutions :
Immunocytochemistry: 1-5 ug/mL, Immunohistochemistry (Paraffin): 1:200, Western Blot: 2 ug/mL
Aliases :
1810014L12Rik; AI115531; AL022956; D11Bhm182e; MAC30; meningioma-associated protein 30; S2R; Sigma intracellular receptor 2; Sigma-2 receptor; Tmem97; Transmembrane protein 97
more info or order :
Invitrogen product webpage
company information
Invitrogen
Thermo Fisher Scientific
81 Wyman Street
Waltham, MA USA 02451
https://www.thermofisher.com
800-678-5599
headquarters: USA